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Database: UniProt
Entry: C6WGX8_ACTMD
LinkDB: C6WGX8_ACTMD
Original site: C6WGX8_ACTMD 
ID   C6WGX8_ACTMD            Unreviewed;       500 AA.
AC   C6WGX8;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   16-JAN-2019, entry version 50.
DE   SubName: Full=NCS1 nucleoside transporter family {ECO:0000313|EMBL:ACU36046.1};
GN   OrderedLocusNames=Amir_2101 {ECO:0000313|EMBL:ACU36046.1};
OS   Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU
OS   3971).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Actinosynnema.
OX   NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU36046.1, ECO:0000313|Proteomes:UP000002213};
RN   [1] {ECO:0000313|EMBL:ACU36046.1, ECO:0000313|Proteomes:UP000002213}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971
RC   {ECO:0000313|Proteomes:UP000002213};
RX   PubMed=21304636; DOI=10.4056/sigs.21137;
RA   Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA   Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D.,
RA   Goodwin L., Pitluck S., Rohde M., Goker M., Pati A., Ivanova N.,
RA   Mavromatis K., Chen A., Palaniappan K., Hauser L., Chang Y.J.,
RA   Jeffries C.C., Brettin T., Detter J.C., Han C., Chain P.,
RA   Tindall B.J., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL   Stand. Genomic Sci. 1:46-53(2009).
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DR   EMBL; CP001630; ACU36046.1; -; Genomic_DNA.
DR   RefSeq; WP_015800935.1; NC_013093.1.
DR   STRING; 446462.Amir_2101; -.
DR   EnsemblBacteria; ACU36046; ACU36046; Amir_2101.
DR   KEGG; ami:Amir_2101; -.
DR   eggNOG; ENOG4105EW8; Bacteria.
DR   eggNOG; COG1953; LUCA.
DR   HOGENOM; HOG000165632; -.
DR   KO; K03457; -.
DR   OMA; FMWIGDG; -.
DR   OrthoDB; 326558at2; -.
DR   BioCyc; AMIR446462:G1GEY-2126-MONOMER; -.
DR   Proteomes; UP000002213; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.4160.10; -; 1.
DR   InterPro; IPR012681; NCS1.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR038271; Pur-cyt_permease_sf.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
DR   TIGRFAMs; TIGR00800; ncs1; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002213};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002213};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     50     71       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     77     97       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    117    139       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    171    189       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    201    219       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    239    260       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    281    305       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    325    347       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    359    377       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    389    414       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    438    457       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    477    494       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   500 AA;  53855 MW;  66655E6F1B4A525E CRC64;
     MALDPSAQIA SDQEGRVDLV DRAAIADSPY YNPELAPVPL EGRTWTTYNF FALWMGMAHN
     IPSYTLAASL VALGMDWVQA LLTITLGNLI VLAPMLLNSH AGTKYGIPFP VFARAFYGVR
     GANLVALLRA FVACAWFGIQ TWVGGKALHV IVGRLAGEAW TGAPVVLGQV WTLWLCFLVF
     WAVQMLVIWR GMEAIRRFEN WTAPLVSVGF LVLLAYVAVK AGGFGPILSE PSKLGWGPDF
     WKVFFPALMG MIAFWSTLSL NMPDFTRFGG SQRKQALGQV LGLPTTMTFI AVVAILTTSG
     AQALYGEAIW DPAELASRFD STAVVLVALV SLVLATVSAN LAANVVSPSY DFSNAFPRRI
     SFAVGGLITG VLGVLIQPWR LISDPGIYIF AWLGFYGGLL ASVAGVLVAG YWVLARTRLE
     LPDLYLSGRG AYWFTGGWNW RAVVATALGS LLAVGGAHGG PFPADGLIPP LKPLYDYNWV
     VGLVVGMAGY LVLAPRKEQA
//
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