ID C6WMW9_ACTMD Unreviewed; 534 AA.
AC C6WMW9;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ACU38482.1};
GN OrderedLocusNames=Amir_4650 {ECO:0000313|EMBL:ACU38482.1};
OS Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinosynnema.
OX NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU38482.1, ECO:0000313|Proteomes:UP000002213};
RN [1] {ECO:0000313|EMBL:ACU38482.1, ECO:0000313|Proteomes:UP000002213}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX PubMed=21304636; DOI=10.4056/sigs.21137;
RA Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL Stand. Genomic Sci. 1:46-53(2009).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001630; ACU38482.1; -; Genomic_DNA.
DR RefSeq; WP_015803369.1; NC_013093.1.
DR AlphaFoldDB; C6WMW9; -.
DR STRING; 446462.Amir_4650; -.
DR KEGG; ami:Amir_4650; -.
DR eggNOG; COG1022; Bacteria.
DR HOGENOM; CLU_000022_45_5_11; -.
DR OrthoDB; 9766486at2; -.
DR Proteomes; UP000002213; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF5; MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ACU38482.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002213}.
FT DOMAIN 34..355
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 534 AA; 58075 MW; 393225ADF6AB5FD2 CRC64;
MGGEDPRIVL EWLRAATTGG VHRVERGGTR FAPWSEVLGD VERVVAHLRE RGIAPRARVG
VRGDNSYEWL VLDLALLELG AVPVAIPVPD FKGRTNSEVA RTYGLVAVFA AKAARSADDG
PAVAPLERLL ELPGFTPDAD PPAPLGKRLP ENDREVFTLA FSSGTAGRVK CLLLAWRGVE
ALVEAQGAAY PMTPEDRVLI ALPLSTFQQR YLCYLAIRNA CGIVLTTASR FLAALEQGRP
TILLGPPNFY EFAHSRYEKL PPHERAALDR AVEPADSLPR EEALRLRREV FRSFHDSYGG
RARLMLVGSA PVRPEMLEFF ARAGFELYQI YGMTEIGYLT WNLPGANRIG SVGRENQPGS
VEIAPDGEVL VTHDVHLCVG YEGEGPEDVE PVFRGPCTIA TGDLGEFVDG HLFLKGRKKN
VVITSGGEKL QIEDLEFDIA KAGGVNRVAL YPAPDGDGYA AAVWYDGDRE AARDAVRPRI
GLVSSRLGAG RRISRIALLP GELTPESPLL NRNLKVNRDA VRVATSAALE PLDA
//
