ID   C6X188_FLAB3            Unreviewed;       323 AA.
AC   C6X188;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=Isochorismate synthase {ECO:0000313|EMBL:ACU08201.1};
DE            EC=5.4.4.2 {ECO:0000313|EMBL:ACU08201.1};
GN   OrderedLocusNames=FIC_01758 {ECO:0000313|EMBL:ACU08201.1};
OS   Flavobacteriaceae bacterium (strain 3519-10).
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae.
OX   NCBI_TaxID=531844 {ECO:0000313|EMBL:ACU08201.1, ECO:0000313|Proteomes:UP000001512};
RN   [1] {ECO:0000313|EMBL:ACU08201.1, ECO:0000313|Proteomes:UP000001512}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3519-10 {ECO:0000313|EMBL:ACU08201.1,
RC   ECO:0000313|Proteomes:UP000001512};
RX   PubMed=18622572; DOI=10.1007/s00792-008-0178-2;
RA   Raymond J.A., Christner B.C., Schuster S.C.;
RT   "A bacterial ice-binding protein from the Vostok ice core.";
RL   Extremophiles 12:713-717(2008).
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DR   EMBL; CP001673; ACU08201.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6X188; -.
DR   STRING; 531844.FIC_01758; -.
DR   KEGG; fba:FIC_01758; -.
DR   eggNOG; COG1169; Bacteria.
DR   HOGENOM; CLU_006493_8_0_10; -.
DR   OrthoDB; 9806579at2; -.
DR   Proteomes; UP000001512; Chromosome.
DR   GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR   InterPro; IPR005801; ADC_synthase.
DR   InterPro; IPR015890; Chorismate_C.
DR   PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR   Pfam; PF00425; Chorismate_bind; 1.
DR   SUPFAM; SSF56322; ADC synthase; 1.
PE   4: Predicted;
KW   Isomerase {ECO:0000313|EMBL:ACU08201.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001512}.
FT   DOMAIN          72..312
FT                   /note="Chorismate-utilising enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00425"
SQ   SEQUENCE   323 AA;  36632 MW;  DDF9AEE63255936E CRC64;
     MLFFSFPFSD IIYATDDSPG RNGVSFLSFD QSEIIGFEGD CKEISIDEFL NKPILTADFS
     TILPHFEQET ESSYTQKLTN VIAFIRENRL KKLVISRRKS VDFNDAQVNL SQTFLNLKTA
     YPNAFVYVFL KDGKCWIGAF SELLGKFNKN TAEFETMALA GTIPVNEEWT RKEIEEQKPV
     AEYILNILKQ YSSTVRVSST ADHLSGNIKH LRTDFKAEIK AEDLENIIAE LHPTPAVCGI
     PKEICTKAIA AFEDHPRKFY AGYIKVETDE SVQYFVNLRC AEFFQNAALV YVGGGITAES
     SPQKEWRETE LKSEAIIKNL SFI
//