ID C6X8X5_METGS Unreviewed; 564 AA.
AC C6X8X5;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Protein serine/threonine phosphatase {ECO:0000313|EMBL:ACT49595.1};
GN OrderedLocusNames=Msip34_0346 {ECO:0000313|EMBL:ACT49595.1};
OS Methylovorus glucosotrophus (strain SIP3-4).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Methylophilaceae; Methylovorus.
OX NCBI_TaxID=582744 {ECO:0000313|EMBL:ACT49595.1, ECO:0000313|Proteomes:UP000002743};
RN [1] {ECO:0000313|Proteomes:UP000002743}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SIP3-4 {ECO:0000313|Proteomes:UP000002743};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Clum A., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Kayluzhnaya M., Chistoserdova L.;
RT "Complete sequence of chromosome of Methylovorus sp. SIP3-4.";
RL Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACT49595.1, ECO:0000313|Proteomes:UP000002743}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SIP3-4 {ECO:0000313|EMBL:ACT49595.1,
RC ECO:0000313|Proteomes:UP000002743};
RX PubMed=21622745; DOI=10.1128/JB.00404-11;
RA Lapidus A., Clum A., Labutti K., Kaluzhnaya M.G., Lim S., Beck D.A.,
RA Glavina Del Rio T., Nolan M., Mavromatis K., Huntemann M., Lucas S.,
RA Lidstrom M.E., Ivanova N., Chistoserdova L.;
RT "Genomes of three methylotrophs from a single niche uncover genetic and
RT metabolic divergence of Methylophilaceae.";
RL J. Bacteriol. 193:3757-3764(2011).
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DR EMBL; CP001674; ACT49595.1; -; Genomic_DNA.
DR RefSeq; WP_015829278.1; NC_012969.1.
DR AlphaFoldDB; C6X8X5; -.
DR STRING; 582744.Msip34_0346; -.
DR KEGG; mei:Msip34_0346; -.
DR eggNOG; COG0515; Bacteria.
DR eggNOG; COG0631; Bacteria.
DR HOGENOM; CLU_034273_0_0_4; -.
DR OrthoDB; 9801841at2; -.
DR Proteomes; UP000002743; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR CDD; cd00143; PP2Cc; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR PANTHER; PTHR24351; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR PANTHER; PTHR24351:SF243; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13672; PP2C_2; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51746; PPM_2; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002743};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 543..562
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..232
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT DOMAIN 265..527
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 564 AA; 63100 MW; FBA92B13D8B20CD5 CRC64;
MSLQLLLGQS TATGPRERNE DFAGMVTPVG MQLQTKGALI ALADGVSGNA GGREAAEMTV
RSILSDYYAT PDTWEVHSAL DKVITAANRW LLAQAAQHKD FAGMASTLSL IVFRGQRFYS
AHVGDTRIYR LRHGELQKLT TDHVWERPDM RHVLKRAIGL DQHLSVDYAD GALQVGDVYA
LMSDGVWDVL DQATLHHVMG LYDNPQLICD ELTRLAIAQG GHDNATVLAA HVVQLGEETL
TDLLAEHRHL RVPPKMKAGD VIDQFEVLSV LHESRASLIY KVRHRITNQL WVLKTLQPLL
AEDRDSCQAL LNEEWLAKRV VSQYLPQVLP LTAEQRSQLY YVMSWHEGAT LQHRLDNGHH
FTTAGITGIG IALLRGLGAL HRLQILHRDI KPANLHMAMD QRLRILDLGV ALSPVTGHIA
SMDNPGTPSF MAPELFDGAG ASVSSDLYAA GVTLYYLLTR KYPYGEIEPF QHPRFGEPVP
PTRYRPEIPR WLENILLKAV ARQPEHRFET AEEMLLALEI GETRPILPPP RTPLIARARL
VKWQWIALVS LMVNFMLLYL LIVS
//
