ID C6XHZ3_LIBAP Unreviewed; 820 AA.
AC C6XHZ3;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=CLIBASIA_01490 {ECO:0000313|EMBL:ACT56886.1};
OS Liberibacter asiaticus (strain psy62).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Liberibacter.
OX NCBI_TaxID=537021 {ECO:0000313|EMBL:ACT56886.1, ECO:0000313|Proteomes:UP000002744};
RN [1] {ECO:0000313|EMBL:ACT56886.1, ECO:0000313|Proteomes:UP000002744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=psy62 {ECO:0000313|Proteomes:UP000002744};
RX PubMed=19589076; DOI=10.1094/MPMI-22-8-1011;
RA Duan Y., Zhou L., Hall D.G., Li W., Doddapaneni H., Lin H., Liu L.,
RA Vahling C.M., Gabriel D.W., Williams K.P., Dickerman A., Sun Y.,
RA Gottwald T.;
RT "Complete genome sequence of citrus huanglongbing bacterium, 'Candidatus
RT Liberibacter asiaticus' obtained through metagenomics.";
RL Mol. Plant Microbe Interact. 22:1011-1020(2009).
RN [2] {ECO:0000313|EMBL:ACT56886.1, ECO:0000313|Proteomes:UP000002744}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=psy62 {ECO:0000313|Proteomes:UP000002744};
RX PubMed=21784907; DOI=10.1128/AEM.05111-11;
RA Zhou L., Powell C.A., Hoffman M.T., Li W., Fan G., Liu B., Lin H., Duan Y.;
RT "Diversity and plasticity of the intracellular plant pathogen and insect
RT symbiont, 'Candidatus Liberibacter asiaticus', revealed by hyper variable
RT prophage genes with intragenic tandem repeats.";
RL Appl. Environ. Microbiol. 77:6663-6673(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP001677; ACT56886.1; -; Genomic_DNA.
DR RefSeq; WP_012778632.1; NC_012985.3.
DR AlphaFoldDB; C6XHZ3; -.
DR STRING; 537021.CLIBASIA_01490; -.
DR GeneID; 66285880; -.
DR KEGG; las:CLIBASIA_01490; -.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_23_1_5; -.
DR OrthoDB; 9801651at2; -.
DR Proteomes; UP000002744; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ACT56886.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:ACT56886.1}.
FT DOMAIN 450..520
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 591..812
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 820 AA; 93210 MW; AD4C0777D3DFC925 CRC64;
MSTDSIISNP EDILTSNCKG NTQDLSKKKI DNGFETEKSK KENPCHDSFE QSNFTDQNQE
SVSNTNYLDS ENTFVFDPIP RTVRFTWNID AHGYLKEISE ELPKTIGNYA FKMIGMRLCD
VSDILHIDPN NHIGDLLKRQ NTWYGKTTLW PIEGTNLYVP IDLAALPIYS RNREFSGFRG
FGIVHVNRVD NDPRALGKRL DKKFSHLHEI KKGHSSVEKE KYDIFSQQSP PPHLRMKNKV
SSLTEYYAHK DDVLKTEKYP LLTSEESSLP EQEDFHTINL NQYTKKQYFG TLQNNSKESF
EYLSHRNHPS LSAYFDEGEN LTPETVDKCP IPFFVYSHGN LFYANPSFLL LTKYKSVDDI
EIAGGLSTLL DAPKLSDNNA IKPVMLYRSD RTCIAASARL HTIQWNRENS LAMTFIPFEK
ANQFPENMPQ NGIEPEDVDT RINKRKMEIE VMQLCSILEA TSDGIAIINR EGIILSTNRA
VSKLFGYPVE DILRKPFTVF LEQNTPSVMN HYLTEILSLD LRQTLEKITL GSTKEEKLLS
LRIIIKKLPF SSCYSLTMHD ISEWKQEKNK LSHAKKIAEK ESSHKSDFLA RVSHEIRTPL
TAIIGFSEVI KNQRFGPLGN PRYIEYANYI DRSGNLVLDI VNDLLDISKI ESGKMNLHFE
PVSLDEAVSE AISLVQLYAN EKRILIRTSF ANNIPRILAD LRSVKQIALN ILSNAIHFTP
SGGQIIISTT HTSNEEVILR VRDTGVGMTN YELEKAMKPF GQIPNSQQIR GEGTGLGLPL
AKAMVDANMG KFYIFSTPAK GTLIEIIFPL YDTSHPHDCI
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