ID C6XLS7_HIRBI Unreviewed; 700 AA.
AC C6XLS7;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with MHYT sensor {ECO:0000313|EMBL:ACT57983.1};
GN OrderedLocusNames=Hbal_0281 {ECO:0000313|EMBL:ACT57983.1};
OS Hirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomonadales;
OC Hyphomonadaceae; Hirschia.
OX NCBI_TaxID=582402 {ECO:0000313|EMBL:ACT57983.1, ECO:0000313|Proteomes:UP000002745};
RN [1] {ECO:0000313|Proteomes:UP000002745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49814 / DSM 5838 / IFAM 1418
RC {ECO:0000313|Proteomes:UP000002745};
RX PubMed=21705585; DOI=10.1128/JB.05453-11;
RG US DOE Joint Genome Institute;
RA Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL J. Bacteriol. 193:4567-4568(2011).
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DR EMBL; CP001678; ACT57983.1; -; Genomic_DNA.
DR AlphaFoldDB; C6XLS7; -.
DR STRING; 582402.Hbal_0281; -.
DR KEGG; hba:Hbal_0281; -.
DR eggNOG; COG3300; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_49_5; -.
DR OrthoDB; 7279500at2; -.
DR Proteomes; UP000002745; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR005330; MHYT_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF03707; MHYT; 2.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50924; MHYT; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU00244};
KW Reference proteome {ECO:0000313|Proteomes:UP000002745};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00244};
KW Transmembrane helix {ECO:0000256|PROSITE-ProRule:PRU00244}.
FT TRANSMEM 16..35
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 47..70
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 82..104
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 111..134
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 146..163
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 175..200
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 212..237
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT DOMAIN 12..199
FT /note="MHYT"
FT /evidence="ECO:0000259|PROSITE:PS50924"
FT DOMAIN 284..416
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 425..675
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 700 AA; 77531 MW; 4E95FAE0FE15A58D CRC64;
MISVVSCIIF EHDLRLVLMA AIMCVVGAIT VVNLFRRSCA SVAHARIAWS ILTSIATGAS
IWSTHFISML AYQAEIPVRF DVILTMVSLL IPMTLMSPLI YLATKMRKQN VSIVIGGAIG
LVVSSIHYLG MAAYRVDGVV EWNTTYVIAS IIIPVVFCTA TFGHFPKYKF MSKRLISIGA
FTVAVVGLHF TAMTAINIIP FNLSDMPMST DAFYGMAMAT AAGGFLVLVT GLVSFVIDSS
TREANSQEIE RLVATDALTG LPNRRSFREH IENTLAGFET NPLSNFAVLY IDINGFKVVN
DTLGYSVGDV VLKTFADRMS ETLSSGEYIA RLGKDEFAAV KVYNSANELE AFVQKVEDSI
EIPIEVEEES IELDLAIGIA CCPTDGHYAD ELTSNAELAL RRAKSNASDS ICYYDANMDD
VVRHHREMVR NLRQAILKNE LQLYYQMQAN VQTGELKGFE ALLRWTHPEK GPISPALFIP
IAEENGLIIQ LGDWVLKQAC KEAALWEKPY KVAVNLSPMQ LMQPNLPKRI HEILLDTGLS
ANRLEIELTE TAIFEDRERS VHVLRQIKAL GVNVALDDFG TGYSSLEVLR SFPFDKIKLD
RFFMDEIETS SVAKAFLRSV LALGRNLSIP VLAEGVETEN QLRILQEEGC DAIQGFLLHK
PSREVPFEHN LDFADTHSVK SAAGPSDNLF SMVKLETRRG
//
