ID   C6XY02_PEDHD            Unreviewed;       652 AA.
AC   C6XY02;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   24-JAN-2024, entry version 64.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   OrderedLocusNames=Phep_2216 {ECO:0000313|EMBL:ACU04420.1};
OS   Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457
OS   / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3).
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=485917 {ECO:0000313|EMBL:ACU04420.1, ECO:0000313|Proteomes:UP000000852};
RN   [1] {ECO:0000313|EMBL:ACU04420.1, ECO:0000313|Proteomes:UP000000852}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 /
RC   NCIMB 9290 / NRRL B-14731 / HIM 762-3
RC   {ECO:0000313|Proteomes:UP000000852};
RX   PubMed=21304637; DOI=10.4056/sigs.22138;
RA   Han C., Spring S., Lapidus A., Del Rio T.G., Tice H., Copeland A.,
RA   Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S.,
RA   Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA   Land M., Hauser L., Chang Y.J., Jeffries C.C., Saunders E., Chertkov O.,
RA   Brettin T., Goker M., Rohde M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P., Detter J.C.;
RT   "Complete genome sequence of Pedobacter heparinus type strain (HIM 762-
RT   3).";
RL   Stand. Genomic Sci. 1:54-62(2009).
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DR   EMBL; CP001681; ACU04420.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6XY02; -.
DR   STRING; 485917.Phep_2216; -.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   KEGG; phe:Phep_2216; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_420246_0_0_10; -.
DR   Proteomes; UP000000852; Chromosome.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000852};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          340..545
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   652 AA;  71440 MW;  BCED0F5C5F9BD86D CRC64;
     MIKLNKDIIL KYIRMKIYRP TAYFCFVLCI SSLLITSCYK EEHFDFPGPY EEANTVNPDS
     LPFPFDVNKQ AGVWLVKNGV PDYGKVLFKG YTDYYPKGDT LSWVKENDGL HMLPHFSFYP
     LSNADHFAGD PNSYKFNWVY SKYFVPVGSG KSFYMYAKVT FGTFNSTAAG LSLGKNWDTG
     GPFTFGLDGN TSTGEPGFFL DLYGKNGITV NPALGWPTVT QVMTPGVPAN MEVVITNGIF
     YVKVNGTLVF TFKMAAERAY FYTPQIRPWR NFVAVHDMYI ESREMYTLDY AMHEYEGSYN
     KIQAPALAKT PNGELLLFAE GRSTPTSAKE RVAQNTMPVG NTDIIMKRSA DGGNTWSNQL
     TVLAGNGSNL TYCFPQVVTT DNGKIILQYS TIGGAFAANS NAFTYDVNSQ RIYQIESNDN
     GLSWTIPVEI TAFKNTAAGY IQGGAVHGIA LKSATYNKRL VMPLTYSTNV VRMALSDDGG
     ITWRLGKAIS GSRLTKATVV ELSDGRLMMV AGHTNTSPKN KLVSYSSDGG DNWTAAANIS
     ADVKTGDYGH LFGGIILKGK DGEILLVNPI NRETDTEVKN SPTYAVAPVV FKSTSNGQAY
     TTVGPLFSRE AYFGYNAPIG NMDGIVLDDG RIVIAGEGGV ESPAEGIVIY KK
//