ID C6XZM8_PEDHD Unreviewed; 594 AA.
AC C6XZM8;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Chloride channel core {ECO:0000313|EMBL:ACU04724.1};
GN OrderedLocusNames=Phep_2520 {ECO:0000313|EMBL:ACU04724.1};
OS Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457
OS / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3).
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=485917 {ECO:0000313|EMBL:ACU04724.1, ECO:0000313|Proteomes:UP000000852};
RN [1] {ECO:0000313|EMBL:ACU04724.1, ECO:0000313|Proteomes:UP000000852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 /
RC NCIMB 9290 / NRRL B-14731 / HIM 762-3
RC {ECO:0000313|Proteomes:UP000000852};
RX PubMed=21304637; DOI=10.4056/sigs.22138;
RA Han C., Spring S., Lapidus A., Del Rio T.G., Tice H., Copeland A.,
RA Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S.,
RA Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.C., Saunders E., Chertkov O.,
RA Brettin T., Goker M., Rohde M., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Detter J.C.;
RT "Complete genome sequence of Pedobacter heparinus type strain (HIM 762-
RT 3).";
RL Stand. Genomic Sci. 1:54-62(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP001681; ACU04724.1; -; Genomic_DNA.
DR RefSeq; WP_015808336.1; NZ_AQGK01000001.1.
DR AlphaFoldDB; C6XZM8; -.
DR STRING; 485917.Phep_2520; -.
DR KEGG; phe:Phep_2520; -.
DR eggNOG; COG0038; Bacteria.
DR eggNOG; COG0517; Bacteria.
DR HOGENOM; CLU_015263_5_1_10; -.
DR OrthoDB; 9812438at2; -.
DR Proteomes; UP000000852; Chromosome.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000852};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 532..592
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 594 AA; 65298 MW; 003BDBE223B86F19 CRC64;
MYVRLVSYID AINQYRKTKI SNRNFLVIAA LIVGILAGLA AALLKSLTHH IEDFLQTGFH
WQYKYYLFFF FPFIGILLSV LYVRRFIRKG KFETGLTPIL YTISKKSSKI EPHNIYSQVI
TAALTVGFGG STGLEAPIVT SGGGIGSVVG RFLGLSYRET TMLLACGAAA GIAGAFNSPI
AGIVFAIEIL LPEFTIPAFI PLLLSAATAA VVARLFYNEQ LFFLVTEGWK MNALIYYVLL
AVLIGLFSIY FKKVNSFIKT SFYKIRNPYK KVVLGGLMLG IMVFLFPTLY GEGYITIKNL
LGGNYTTLLS NSIFAEYSSL PWVIILFTVV TVFAKSAATL ITLSAGGNGG IFAPSLIMGG
LIGFAVAFAI NTLGLAHLSV ANFIVAGMAA SLSAIMHAPL TGIFLIAEIT GGYVLMVPLM
ITSAIAYLIN RSKHKYSIYT QPLAERGELL SLEDKDATVL NMMKLRHLLE HDYLVLNEND
LISDRLNEIL QSKRNLFPVV GNEQDFKGLL YVEDLLKKGI SNSDTLAVQD LMQTAPDVAV
ISDSLKHLLQ KMEKENAWLL PVLDEQGKYL GLVSKTAIFN KYRALLSRQA DYMG
//
