ID C7BMS1_PHOAA Unreviewed; 559 AA.
AC C7BMS1;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Similar to pyocin s2 and s1 {ECO:0000313|EMBL:CAQ82907.1};
GN OrderedLocusNames=PAU_00815 {ECO:0000313|EMBL:CAQ82907.1};
OS Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77)
OS (Xenorhabdus luminescens (strain 2)).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=553480 {ECO:0000313|EMBL:CAQ82907.1, ECO:0000313|Proteomes:UP000002747};
RN [1] {ECO:0000313|EMBL:CAQ82907.1, ECO:0000313|Proteomes:UP000002747}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43949 / 3105-77 {ECO:0000313|Proteomes:UP000002747};
RX PubMed=19583835; DOI=10.1186/1471-2164-10-302;
RA Wilkinson P., Waterfield N.R., Crossman L., Corton C.,
RA Sanchez-Contreras M., Vlisidou I., Barron A., Bignell A., Clark L.,
RA Ormond D., Mayho M., Bason N., Smith F., Simmonds M., Churcher C.,
RA Harris D., Thompson N.R., Quail M., Parkhill J., ffrench-Constant R.H.;
RT "Comparative genomics of the emerging human pathogen Photorhabdus
RT asymbiotica with the insect pathogen Photorhabdus luminescens.";
RL BMC Genomics 10:302-302(2009).
CC -!- FUNCTION: Colicins are polypeptide toxins produced by and active
CC against E.coli and closely related bacteria.
CC {ECO:0000256|ARBA:ARBA00003197}.
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DR EMBL; FM162591; CAQ82907.1; -; Genomic_DNA.
DR AlphaFoldDB; C7BMS1; -.
DR SMR; C7BMS1; -.
DR STRING; 291112.PAU_00815; -.
DR KEGG; pay:PAU_00815; -.
DR eggNOG; COG4104; Bacteria.
DR Proteomes; UP000002747; Chromosome.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR CDD; cd14744; PAAR_CT_2; 1.
DR InterPro; IPR008727; PAAR_motif.
DR InterPro; IPR016128; Pyosin/cloacin_T_dom.
DR InterPro; IPR036302; Pyosin/cloacin_T_dom_sf.
DR PANTHER; PTHR37465; -; 1.
DR PANTHER; PTHR37465:SF1; BACTERIAL TOXIN 44 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF05488; PAAR_motif; 1.
DR Pfam; PF06958; Pyocin_S; 1.
DR SUPFAM; SSF69369; Cloacin translocation domain; 1.
PE 4: Predicted;
KW Antibiotic {ECO:0000256|ARBA:ARBA00023022};
KW Antimicrobial {ECO:0000256|ARBA:ARBA00022529};
KW Bacteriocin {ECO:0000256|ARBA:ARBA00023048}.
FT DOMAIN 284..422
FT /note="Pyosin/cloacin translocation"
FT /evidence="ECO:0000259|Pfam:PF06958"
FT REGION 113..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 150..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..202
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 559 AA; 61701 MW; BF07E645FA18B790 CRC64;
MAIGYFLLVG DKTTCGGQII TGDHTMTFNG RATAREGDKV ICGKHPGTYM IVGGVSDVFD
MVRKLAGTLD SVSTCPCRAR FINSERDSYE KQEQPNHPAT APVNMAAQNI SSPVKEAESV
QSGPPPVIKA PPPTPVFTKS CLRGKGCTDA GTDAEPADNF GRMGIYQVSS SPAPVTPPKP
EPPPPSKKHP PEPDKSQDKK LPWYKRWLSD GKDKTEAAAT AVAATARSAV AEGEALAMRY
IGGSAISAGR WLAAPNPVTV GLMGLFYSPS LNQGEEDYLS QYQLRQIAEQ FGKALTRVRF
RWIRDEESGR MTVQGYHVSP ESGLDEVPVH VMRLNRTTGN YEFWEPGENR PTILWTPNEQ
EFKVPAHTGN EEPPFIPSQI TVLPIPDKVG SDIESLPMPE EKDFRDYILV LPIPNMPPVY
VYLSKPPVKP LEVGEYQDLA GRSRNDGLDI DHIPSKAALR EYLIRTYGEK IQEQDIKNAL
KEGISIAIPK RVHQKYSETY GDRNIPEKTV KDSMNLKAAV DSNFNAQVLG LREEGYTDEQ
LGKALGQLHR LNKEKGWYE
//
