ID C7BQD4_PHOAA Unreviewed; 787 AA.
AC C7BQD4;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Hypothetical membrane protein ycai {ECO:0000313|EMBL:CAQ84909.1};
GN Name=ycaI {ECO:0000313|EMBL:CAQ84909.1};
GN OrderedLocusNames=PAU_02820 {ECO:0000313|EMBL:CAQ84909.1};
OS Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77)
OS (Xenorhabdus luminescens (strain 2)).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=553480 {ECO:0000313|EMBL:CAQ84909.1, ECO:0000313|Proteomes:UP000002747};
RN [1] {ECO:0000313|EMBL:CAQ84909.1, ECO:0000313|Proteomes:UP000002747}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43949 / 3105-77 {ECO:0000313|Proteomes:UP000002747};
RX PubMed=19583835; DOI=10.1186/1471-2164-10-302;
RA Wilkinson P., Waterfield N.R., Crossman L., Corton C.,
RA Sanchez-Contreras M., Vlisidou I., Barron A., Bignell A., Clark L.,
RA Ormond D., Mayho M., Bason N., Smith F., Simmonds M., Churcher C.,
RA Harris D., Thompson N.R., Quail M., Parkhill J., ffrench-Constant R.H.;
RT "Comparative genomics of the emerging human pathogen Photorhabdus
RT asymbiotica with the insect pathogen Photorhabdus luminescens.";
RL BMC Genomics 10:302-302(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FM162591; CAQ84909.1; -; Genomic_DNA.
DR AlphaFoldDB; C7BQD4; -.
DR STRING; 291112.PAU_02820; -.
DR KEGG; pay:PAU_02820; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR Proteomes; UP000002747; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 541..722
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 787 AA; 91265 MW; 3A4486D76557D1B7 CRC64;
MLKKVNEQRW IRMWLSVLIN RITINWKQPI PVISVNQAAI AIIIGIIPLL FLPELPQKWQ
MIAFVLLALF CLFLPFCICR MISISLLAFL VGCWQGNHLL EQIIYLSERG HISQAIVESL
SLGDEGKNKV LLRLIKTEDK IIFPPLYVSA YWDFFPDSLC AGQKWQLKMK LRPVHSQLNQ
GGYDSQRRAL AVRQPLTGKV IHAELIDEKC NLRQQLVSHI APAIRELKHR GIAMALAFGE
RQWLNKEDNL LLQQTGTAHL MAISGLHITV ASMFGWWMAR LLQLSFPLHW IGHRFPLISG
WIVAIMYVWL SGWGIPAIRA LLGLTLWLYL RHRNILCFPW QWALWTAAII LLFDPLTVLS
DSFWLSFFAV MALMFWFFWA PLGEPFRYGW KWLWLRGLYM QMGMMLMLIP LQLLLFHGVN
FSALFANFWA VPIISFITVP LIMLALISTF CPFIHTLLWQ LVDYSVTFSL IPLPVLQQSW
SETGSFPILI TFIGWFVVIV WRFAWWQSYK LLIGISLGVM LCYLRRNEEY LWRFSMLDVG
HGLAVIIEKN GKALIFDTGN RWETGSVAER VITPYLRWHR LTPEQIIISH NHLDHTGGLE
FLQRKYPDVS VRSPLTDNKH LPCIRGEQWQ WQGLNFRVLW PPERVVQAGN NESCVIRVED
GKHSLLLTGD LEKQGEYKLL GIEKDNLRST ILQVPHHGSN TSSTAAFIRK VAPQYAFASV
ARYSPWRLPS IKVLQRYRKA GVEWRSTAVS GQITGCFYGD HVEITGYRQQ IMSRWYHQWF
GIRGDHE
//
