ID C7BS20_PHOAA Unreviewed; 231 AA.
AC C7BS20;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Tol-Pal system protein TolQ {ECO:0000256|HAMAP-Rule:MF_02202};
GN Name=tolQ {ECO:0000256|HAMAP-Rule:MF_02202,
GN ECO:0000313|EMBL:CAQ85050.1};
GN OrderedLocusNames=PAU_02962 {ECO:0000313|EMBL:CAQ85050.1};
OS Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77)
OS (Xenorhabdus luminescens (strain 2)).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=553480 {ECO:0000313|EMBL:CAQ85050.1, ECO:0000313|Proteomes:UP000002747};
RN [1] {ECO:0000313|EMBL:CAQ85050.1, ECO:0000313|Proteomes:UP000002747}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43949 / 3105-77 {ECO:0000313|Proteomes:UP000002747};
RX PubMed=19583835; DOI=10.1186/1471-2164-10-302;
RA Wilkinson P., Waterfield N.R., Crossman L., Corton C.,
RA Sanchez-Contreras M., Vlisidou I., Barron A., Bignell A., Clark L.,
RA Ormond D., Mayho M., Bason N., Smith F., Simmonds M., Churcher C.,
RA Harris D., Thompson N.R., Quail M., Parkhill J., ffrench-Constant R.H.;
RT "Comparative genomics of the emerging human pathogen Photorhabdus
RT asymbiotica with the insect pathogen Photorhabdus luminescens.";
RL BMC Genomics 10:302-302(2009).
CC -!- FUNCTION: Part of the Tol-Pal system, which plays a role in outer
CC membrane invagination during cell division and is important for
CC maintaining outer membrane integrity. Required, with TolR, for the
CC proton motive force-dependent activation of TolA and for TolA-Pal
CC interaction. {ECO:0000256|HAMAP-Rule:MF_02202}.
CC -!- SUBUNIT: The Tol-Pal system is composed of five core proteins: the
CC inner membrane proteins TolA, TolQ and TolR, the periplasmic protein
CC TolB and the outer membrane protein Pal. They form a network linking
CC the inner and outer membranes and the peptidoglycan layer.
CC {ECO:0000256|HAMAP-Rule:MF_02202}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_02202}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_02202}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ExbB/TolQ family.
CC {ECO:0000256|ARBA:ARBA00010442, ECO:0000256|HAMAP-Rule:MF_02202}.
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DR EMBL; FM162591; CAQ85050.1; -; Genomic_DNA.
DR AlphaFoldDB; C7BS20; -.
DR STRING; 291112.PAU_02962; -.
DR KEGG; pay:PAU_02962; -.
DR eggNOG; COG0811; Bacteria.
DR Proteomes; UP000002747; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043213; P:bacteriocin transport; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR HAMAP; MF_02202; TolQ; 1.
DR InterPro; IPR002898; MotA_ExbB_proton_chnl.
DR InterPro; IPR014163; Tol-Pal_TolQ.
DR NCBIfam; TIGR02796; tolQ; 1.
DR PANTHER; PTHR30625; PROTEIN TOLQ; 1.
DR PANTHER; PTHR30625:SF3; TOL-PAL SYSTEM PROTEIN TOLQ; 1.
DR Pfam; PF01618; MotA_ExbB; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP-
KW Rule:MF_02202};
KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP-
KW Rule:MF_02202};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519, ECO:0000256|HAMAP-
KW Rule:MF_02202};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_02202};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_02202};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_02202};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_02202}.
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02202"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02202"
FT TRANSMEM 171..192
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_02202"
FT DOMAIN 80..207
FT /note="MotA/TolQ/ExbB proton channel"
FT /evidence="ECO:0000259|Pfam:PF01618"
SQ SEQUENCE 231 AA; 25720 MW; 0E0C1AF8CCE77922 CRC64;
MADMNILDLF LKAGLLVQLI MLILICFSIA SWAIIIQRTK ILNAATREAE AFEDKFWSGI
ELSRLYKESQ SRRDSLGGTE QIFYSGFKEF ARLHHANNHA PEAVVTGASR AMRISMNREL
ETLESHIPFL GTVGSISPYI GLFGTVWGIM HAFIALGAVK QATLQMVAPG IAEALIATAI
GLFAAIPAVM AYNRLNQRVN KLEQNYDNFM EEFLAILHRQ AFAVENKAEN K
//
