ID   C7D893_9RHOB            Unreviewed;       308 AA.
AC   C7D893;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   24-JAN-2024, entry version 46.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EET46234.1};
DE            EC=1.3.1.12 {ECO:0000313|EMBL:EET46234.1};
GN   ORFNames=TR2A62_3293 {ECO:0000313|EMBL:EET46234.1};
OS   Thalassobium sp. R2A62.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Thalassobium.
OX   NCBI_TaxID=633131 {ECO:0000313|EMBL:EET46234.1, ECO:0000313|Proteomes:UP000004701};
RN   [1] {ECO:0000313|EMBL:EET46234.1, ECO:0000313|Proteomes:UP000004701}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R2A62 {ECO:0000313|EMBL:EET46234.1,
RC   ECO:0000313|Proteomes:UP000004701};
RA   Suzuki M., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG697169; EET46234.1; -; Genomic_DNA.
DR   RefSeq; WP_009157309.1; NZ_GG697169.2.
DR   AlphaFoldDB; C7D893; -.
DR   STRING; 633131.TR2A62_3293; -.
DR   eggNOG; COG0287; Bacteria.
DR   HOGENOM; CLU_055968_0_1_5; -.
DR   OrthoDB; 9802008at2; -.
DR   Proteomes; UP000004701; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:EET46234.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004701}.
FT   DOMAIN          6..296
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   308 AA;  32919 MW;  120764997D7233F0 CRC64;
     MSELYDRVAL IGLGLIASSI AHGIRRANLA HEIVGYAKSE ASRTTAREIG LCDVVTDTAA
     DAVKGADLVI LCVPVGVMGG IAVEIAPHLM DGATVSDVGS VKRAVIDAVG PALPDNVHFI
     PAHPIAGTEK SGPTSGFAEL FDNRWCLIVP AGENVDRVAV SRLTNFWEGL GSNVNVMDAD
     HHDLVLSVTS HAPHLIAYTM VGVADDLARV SESEVINYSA SGFRDFTRIA ASDPTMWRDV
     FLNNKEATLE VLGRFTEELF ALQRAIRTGD GELLHAYFTR TRALRRGIVE AGQDTEAANF
     GRQDGGEN
//