ID   C7D9U8_9RHOB            Unreviewed;       350 AA.
AC   C7D9U8;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   24-JAN-2024, entry version 62.
DE   RecName: Full=alcohol dehydrogenase {ECO:0000256|ARBA:ARBA00013190};
DE            EC=1.1.1.1 {ECO:0000256|ARBA:ARBA00013190};
GN   ORFNames=TR2A62_3576 {ECO:0000313|EMBL:EET47585.1};
OS   Thalassobium sp. R2A62.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Thalassobium.
OX   NCBI_TaxID=633131 {ECO:0000313|EMBL:EET47585.1, ECO:0000313|Proteomes:UP000004701};
RN   [1] {ECO:0000313|EMBL:EET47585.1, ECO:0000313|Proteomes:UP000004701}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R2A62 {ECO:0000313|EMBL:EET47585.1,
RC   ECO:0000313|Proteomes:UP000004701};
RA   Suzuki M., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; GG697169; EET47585.1; -; Genomic_DNA.
DR   RefSeq; WP_009158657.1; NZ_GG697169.2.
DR   AlphaFoldDB; C7D9U8; -.
DR   STRING; 633131.TR2A62_3576; -.
DR   eggNOG; COG1064; Bacteria.
DR   HOGENOM; CLU_026673_11_2_5; -.
DR   OrthoDB; 5295340at2; -.
DR   Proteomes; UP000004701; Unassembled WGS sequence.
DR   GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd05284; arabinose_DH_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42940; ALCOHOL DEHYDROGENASE 1-RELATED; 1.
DR   PANTHER; PTHR42940:SF8; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:EET47585.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004701};
KW   Zinc {ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          11..348
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   350 AA;  37225 MW;  E17CA66F78A38D68 CRC64;
     MKAQVLHTYD DELTAENWLS YEDVPDPVIS KGSDVIVRVG GAGVCRTDLH VIEGVWRPHM
     DPDGDALLPL ILGHENAGWI EEIGSEVEGL KKGDPVIVHP KISNGTCIAC RRGEDMHGEG
     SFPGLDSNGG YAEALVTSAR NLIALPKLLK PKEVAPYSDA GLTAYRAAKK ATRHLMPGQY
     AVVIGAGGLG HIAIQVLRAM CAAEIIVVDT SDASLKLAQE CGADHLIRAD GGEVEAVFSL
     TKGHGAEAVL DFVGEKGTTA KGIAMTRAAG SYYVVGYGEN VQVPTVDLVI TEKNIIGNLV
     GTWAELTELM ELAHRGLVNL ETHEFKLEDA NDALRALHHG KIKGRAVLVP
//