ID C7M8Q9_CAPOD Unreviewed; 945 AA.
AC C7M8Q9;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN OrderedLocusNames=Coch_1893 {ECO:0000313|EMBL:ACU93438.1};
OS Capnocytophaga ochracea (strain ATCC 27872 / DSM 7271 / JCM 12966 / NCTC
OS 12371 / VPI 2845) (Bacteroides ochraceus).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Capnocytophaga.
OX NCBI_TaxID=521097 {ECO:0000313|EMBL:ACU93438.1, ECO:0000313|Proteomes:UP000006650};
RN [1] {ECO:0000313|EMBL:ACU93438.1, ECO:0000313|Proteomes:UP000006650}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27872 / DSM 7271 / JCM 12966 / VPI 2845
RC {ECO:0000313|Proteomes:UP000006650};
RX PubMed=21304645; DOI=10.4056/sigs.15195;
RA Mavrommatis K., Gronow S., Saunders E., Land M., Lapidus A., Copeland A.,
RA Glavina Del Rio T., Nolan M., Lucas S., Chen F., Tice H., Cheng J.F.,
RA Bruce D., Goodwin L., Pitluck S., Pati A., Ivanova N., Chen A.,
RA Palaniappan K., Chain P., Hauser L., Chang Y.J., Jeffries C.D., Brettin T.,
RA Detter J.C., Han C., Bristow J., Goker M., Rohde M., Eisen J.A.,
RA Markowitz V., Kyrpides N.C., Klenk H.P., Hugenholtz P.;
RT "Complete genome sequence of Capnocytophaga ochracea type strain (VPI
RT 2845).";
RL Stand. Genomic Sci. 1:101-109(2009).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; CP001632; ACU93438.1; -; Genomic_DNA.
DR RefSeq; WP_015782914.1; NC_013162.1.
DR AlphaFoldDB; C7M8Q9; -.
DR STRING; 521097.Coch_1893; -.
DR GeneID; 29676714; -.
DR KEGG; coc:Coch_1893; -.
DR eggNOG; COG0178; Bacteria.
DR HOGENOM; CLU_001370_0_2_10; -.
DR Proteomes; UP000006650; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd03271; ABC_UvrA_II; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006650};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 617..945
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 945 AA; 105754 MW; 13B15A2092BCA1D8 CRC64;
MKKKTNNVTP TDVLEVQGAR VHNLKNIDLT IPREKLVVFT GLSGSGKSSL AFDTIYAEGQ
RRYIETFSAY ARQFLGGLER PDVDKIDGLS PVIAIEQKTT SKSPRSTVGT ITEIYDFLRL
LFARASDAYS YATGEKMVSY TDSQIQELIT KEYKGKRINL LAPVVQSRKG HYRELFEQIA
KQGFVKVRTD GEIRDIEKGM KLDRYKTHDI EIVIDRMQID DTDDTQKRLQ ESIKIAMNYG
NDVLMVLEHD QKKAHYFSRH LMCPSSGISY PLPEPNTFSF NSPKGMCPHC NGLGEVQEIN
LSKIIPDPSI SIKNGGITAV GEQKNTWIFK QLALIVQKFG HKLSDPINSL PKEAMDIILY
GGKDKYAIKS EVLGITRNFE IDFEGIINFI KSQHENADMA AIKRWAEEFM DTIPCEDCHG
TRLRKEALYF KIADKNIAEL SALDITDLLA WFKSLPKHLS TKQHKIAEEI IKEITTRLQF
LIDVGLTYLA LNRSSKSLSG GEAQRIRLAT QIGSQLTGVL YILDEPSIGL HQRDNKRLIN
SLKSLRDIGN SVIVVEHDEE MIQEADYVVD IGPKAGVNGG DIIFQGTPKE LLKANTITAD
YMSGRKQIEI PTQRRKGNGK EIILKGCTGN NLKNVTVKFP LGVMIGVTGV SGSGKSTLIN
ETLYPILNAH FFNGIKKPMP YKSIEGLEHI DKVIDIDQSP IGRTPRSNPA TYTGVFSEIR
NLFTQVPEAQ IRGYKPGRFS FNVKEGRCES CEGSGLKVIE MNFLPDVYVP CETCKGKRFN
RETLEVRYKG KSIADVLDMT ISEAVKFFEP IPKIYRKLKT IEEVGLGYIT LGQQSTTLSG
GEAQRVKLAT ELSKIDTGNT FYILDEPTTG LHFDDVKVLL EVLDRLVDKG NTVLVIEHNL
DVIKKVDYII DIGYDGGKAG GEVIAFGTPE EVAKNKKSFT AEYLR
//
