ID C7MB38_BRAFD Unreviewed; 374 AA.
AC C7MB38;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Transcriptional regulator/sugar kinase {ECO:0000313|EMBL:ACU86925.1};
GN OrderedLocusNames=Bfae_31650 {ECO:0000313|EMBL:ACU86925.1};
OS Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / JCM 11609 / LMG
OS 19847 / NBRC 14762 / NCIMB 9860 / 6-10).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC Brachybacterium.
OX NCBI_TaxID=446465 {ECO:0000313|EMBL:ACU86925.1, ECO:0000313|Proteomes:UP000001919};
RN [1] {ECO:0000313|EMBL:ACU86925.1, ECO:0000313|Proteomes:UP000001919}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43885 / DSM 4810 / JCM 11609 / LMG 19847 / NBRC 14762 /
RC NCIMB 9860 / 6-10 {ECO:0000313|Proteomes:UP000001919};
RX PubMed=21304631; DOI=10.4056/sigs.492;
RA Lapidus A., Pukall R., Labuttii K., Copeland A., Del Rio T.G., Nolan M.,
RA Chen F., Lucas S., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S.,
RA Rohde M., Goker M., Pati A., Ivanova N., Mavrommatis K., Chen A.,
RA Palaniappan K., D'haeseleer P., Chain P., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Brachybacterium faecium type strain
RT (Schefferle 6-10).";
RL Stand. Genomic Sci. 1:3-11(2009).
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
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DR EMBL; CP001643; ACU86925.1; -; Genomic_DNA.
DR RefSeq; YP_003156515.1; NC_013172.1.
DR AlphaFoldDB; C7MB38; -.
DR STRING; 446465.Bfae_31650; -.
DR KEGG; bfa:Bfae_31650; -.
DR PATRIC; fig|446465.5.peg.3132; -.
DR eggNOG; COG1940; Bacteria.
DR HOGENOM; CLU_036604_13_3_11; -.
DR OrthoDB; 37575at2; -.
DR Proteomes; UP000001919; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF00480; ROK; 2.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:ACU86925.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001919};
KW Transferase {ECO:0000313|EMBL:ACU86925.1}.
FT DOMAIN 23..60
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|Pfam:PF09339"
SQ SEQUENCE 374 AA; 38202 MW; C05A7933405BF1AA CRC64;
MAMPPPNPSA MRRANARDCT VVLREAERAL TLAEIAAATG LSRPTVDAVL EELQATGIVV
PAPAAASGSA GRPARRFRFA PSAATVAALD IGARTVRCIV ADAAGRELAR GEAPMQGSDP
IAPLVQAVRG TGRAPSAVGV AVPGILDPAG HVSRSLAAPA LEGVDLAGAL AERLGCPVEV
DNDIKLAALA EHHLGPAADS IVLIQLGHRV SVAVIVGGAI LQGAHRLAGE LGSQRGMRWT
DSSVRGRLTW STGDDAQELL ERAAAGDPGA VQEVEEFCAQ IAPRLATVLL TVDPERVVVG
GGLSRAGETL LAPLRRAVGR LLMTEHAPEV VPARLTTDGA LVGALGLGFA HGSARLTGVP
EVPAPWHRFD AGLS
//
