ID C7MBB4_BRAFD Unreviewed; 446 AA.
AC C7MBB4;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Predicted Zn-dependent peptidase {ECO:0000313|EMBL:ACU84887.1};
GN OrderedLocusNames=Bfae_10390 {ECO:0000313|EMBL:ACU84887.1};
OS Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / JCM 11609 / LMG
OS 19847 / NBRC 14762 / NCIMB 9860 / 6-10).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC Brachybacterium.
OX NCBI_TaxID=446465 {ECO:0000313|EMBL:ACU84887.1, ECO:0000313|Proteomes:UP000001919};
RN [1] {ECO:0000313|EMBL:ACU84887.1, ECO:0000313|Proteomes:UP000001919}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43885 / DSM 4810 / JCM 11609 / LMG 19847 / NBRC 14762 /
RC NCIMB 9860 / 6-10 {ECO:0000313|Proteomes:UP000001919};
RX PubMed=21304631; DOI=10.4056/sigs.492;
RA Lapidus A., Pukall R., Labuttii K., Copeland A., Del Rio T.G., Nolan M.,
RA Chen F., Lucas S., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S.,
RA Rohde M., Goker M., Pati A., Ivanova N., Mavrommatis K., Chen A.,
RA Palaniappan K., D'haeseleer P., Chain P., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Brachybacterium faecium type strain
RT (Schefferle 6-10).";
RL Stand. Genomic Sci. 1:3-11(2009).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001643; ACU84887.1; -; Genomic_DNA.
DR RefSeq; WP_012804661.1; NC_013172.1.
DR RefSeq; YP_003154477.1; NC_013172.1.
DR AlphaFoldDB; C7MBB4; -.
DR STRING; 446465.Bfae_10390; -.
DR KEGG; bfa:Bfae_10390; -.
DR PATRIC; fig|446465.5.peg.1038; -.
DR eggNOG; COG0612; Bacteria.
DR HOGENOM; CLU_009902_3_3_11; -.
DR OrthoDB; 9811314at2; -.
DR Proteomes; UP000001919; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR11851:SF149; GH01077P; 1.
DR PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001919}.
FT DOMAIN 34..156
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 187..378
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
FT REGION 232..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 47635 MW; 3154BACA4F2C4D48 CRC64;
MPLDLSYDDP ASDVLLDAAT GVRRSILPGG VRLLTQTDRS VRSATIGLWL PVGSRDETPA
HAGSTHVLEH LLFKGTPRRS AMDIATAFDE VGGDSNALTA KEHTLYYGRV RSSDIPMAVD
VLTDMITASL LEQDALATER EVILEELAMA EDDPGDIGYE TFLADVLGPD TAIGRPVGGT
AASVEALTIE DVRAHFTEHY RPDNLVVTAV GDLDHDELAG LLQDGLRRGG WELEPGRLPS
RRQRPAHPDA SGAAAGSAAD VAALAPHRLG RPTEQNHIYL GGRGLTALSE DRHALSVLMS
VLGGGMSSRL FQNIREQRGL AYSVYSFSAG YRDAGLFGMY AACRPGRTTQ VVELLAEELA
RMGERGIDEL ELARAKGQIT GSFALGLEDT SSRMGRLGTI ELVHGRYTSV DETLERIAAV
GAGDVRALAA RLADSFSTRV EVGPES
//
