ID   C7MHN7_BRAFD            Unreviewed;      1269 AA.
AC   C7MHN7;
DT   13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT   13-OCT-2009, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   SubName: Full=Glycosyl/glycerophosphate transferase, teichoic acid biosynthesis {ECO:0000313|EMBL:ACU86554.1};
GN   OrderedLocusNames=Bfae_27880 {ECO:0000313|EMBL:ACU86554.1};
OS   Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / JCM 11609 / LMG
OS   19847 / NBRC 14762 / NCIMB 9860 / 6-10).
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC   Brachybacterium.
OX   NCBI_TaxID=446465 {ECO:0000313|EMBL:ACU86554.1, ECO:0000313|Proteomes:UP000001919};
RN   [1] {ECO:0000313|EMBL:ACU86554.1, ECO:0000313|Proteomes:UP000001919}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43885 / DSM 4810 / JCM 11609 / LMG 19847 / NBRC 14762 /
RC   NCIMB 9860 / 6-10 {ECO:0000313|Proteomes:UP000001919};
RX   PubMed=21304631; DOI=10.4056/sigs.492;
RA   Lapidus A., Pukall R., Labuttii K., Copeland A., Del Rio T.G., Nolan M.,
RA   Chen F., Lucas S., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S.,
RA   Rohde M., Goker M., Pati A., Ivanova N., Mavrommatis K., Chen A.,
RA   Palaniappan K., D'haeseleer P., Chain P., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Brachybacterium faecium type strain
RT   (Schefferle 6-10).";
RL   Stand. Genomic Sci. 1:3-11(2009).
CC   -!- SIMILARITY: Belongs to the CDP-glycerol glycerophosphotransferase
CC       family. {ECO:0000256|ARBA:ARBA00010488}.
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DR   EMBL; CP001643; ACU86554.1; -; Genomic_DNA.
DR   RefSeq; YP_003156144.1; NC_013172.1.
DR   AlphaFoldDB; C7MHN7; -.
DR   STRING; 446465.Bfae_27880; -.
DR   CAZy; GT4; Glycosyltransferase Family 4.
DR   KEGG; bfa:Bfae_27880; -.
DR   PATRIC; fig|446465.5.peg.2749; -.
DR   eggNOG; COG0438; Bacteria.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG1887; Bacteria.
DR   HOGENOM; CLU_265372_0_0_11; -.
DR   OrthoDB; 8549922at2; -.
DR   Proteomes; UP000001919; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0047355; F:CDP-glycerol glycerophosphotransferase activity; IEA:InterPro.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR   GO; GO:0019350; P:teichoic acid biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd03811; GT4_GT28_WabH-like; 1.
DR   Gene3D; 3.40.50.11820; -; 1.
DR   Gene3D; 3.40.50.12580; -; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR007554; Glycerophosphate_synth.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR043148; TagF_C.
DR   InterPro; IPR043149; TagF_N.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR37316; TEICHOIC ACID GLYCEROL-PHOSPHATE PRIMASE; 1.
DR   PANTHER; PTHR37316:SF3; TEICHOIC ACID GLYCEROL-PHOSPHATE TRANSFERASE; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   Pfam; PF04464; Glyphos_transf; 1.
DR   Pfam; PF13432; TPR_16; 2.
DR   SMART; SM00028; TPR; 5.
DR   SUPFAM; SSF81901; HCP-like; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 2.
DR   PROSITE; PS50005; TPR; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001919};
KW   Teichoic acid biosynthesis {ECO:0000256|ARBA:ARBA00022944};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ACU86554.1}.
FT   REPEAT          266..299
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   DOMAIN          1097..1205
FT                   /note="Glycosyl transferase family 1"
FT                   /evidence="ECO:0000259|Pfam:PF00534"
FT   REGION          117..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1269 AA;  141905 MW;  4A953AC8548D9CFD CRC64;
     MGAYFEHRGK FAEARKWYAR AAAPDDAEAN FRIGNLEYRS ENYHEAIPFL EMAVEGGYAS
     LQSVKRLAVS LERTGDAYGA ERIARRAAEQ NPSEPEYGEI LASIQNRNAQ QELKQLKLEK
     SDSAQSDESG KSTKSPELNR DDPAWLRAEV LASRRGERSN DANWTYHFAT VLEEAGRLHD
     AALAFDDACS LSPRSWWWYR CGRAFAASGN LEASRVRYAR AVDGDRKLDS NKWGIGVFHE
     EAKCWDFAAL DFERAALDAA EVWRRAGLYY RAGRNHLLAM DFQSAEQCLR RALTLRPGNT
     AWARMLADAL ELQDKLEEAA EVLELLARSG ELSASAERSL EWARGRIHYK MGDNELAIQH
     LRASLGDDSE RSTDPSGMDV PGVDVPDVDA HPEWQASSLD GNPFMFHGST DRRGHVERSR
     IAGALRHESL RMDCLRKAQI LSSTNDEEIS TSYSTLLARS GDMKKATEVL LRTRVFWGPY
     PHGFARPKPG TYAYQLAAYM EWRENLPVDP EVILYETNLG LSIDCNPLAL CRHLLSGENQ
     YVHVWAVDGD VPIPIDLLEH NDILVVQKDS LQYTRLLATA KYLINNSTFP TYFSRRQEQK
     YLMTWHGTPL KTLAKDMKEP LVHLNMARNY LQASMAIFPN EHTRHVLIEG TDVHGLLSAE
     VEITGYPRND ALAKLLPSDV PHQGARVLYA PTWREDSELE NQVEELLRVR DAIIEAGHRP
     LLRAHHYVES AATAVDPEIQ FVPRRTPTND LLPEVDILIT DFSSIYFDFA ITGRPMLFYT
     PDWERYAATR GMYFSRAHFP GPICDSLDEL RSALVTPTVD SPTRQEFLDE FAPNDDGGAA
     ERVCRAFFSE QEPKQENALS EKSPAHERGV LIRQAFIPNG MTSSFVNLVT TLSERSVPVT
     VLTDGRAVQE DTGRQSTLAK LPASARVIGR VGMQPKTMLQ YHASIASRKN AGAPSKSLRY
     IIDAMYRAEA HRVLPVTGFI SAIEFDGYSE FMARVVRAIG ECSYSTAIYL HNDIRDEIRL
     RMPELKGVVE IVPEFDHVVA VSEGSARVNA EKLGSAYGID TSRFTYARNL IRPEHIKSQS
     EIPLPEDVVA FADSANLLLV QVGRISPEKN HAFSVEVIDE LQDLGIHAKL LIVGDGPLAP
     MVSNMVTEKN LDEFVYMAGW VENPYPYIAR ADAMVLPSFH EGQPMVILEA QTIGTPVIGS
     DISSLQAMGA DGPETLLPLA VSDWVSELRA RYDSDRTHST GFDGDSYVEM ALEEFCAATG
     VEVPSRGSR
//