ID C7MP11_CRYCD Unreviewed; 581 AA.
AC C7MP11;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Cell division protein FtsI/penicillin-binding protein 2 {ECO:0000313|EMBL:ACU94651.1};
GN OrderedLocusNames=Ccur_09550 {ECO:0000313|EMBL:ACU94651.1};
OS Cryptobacterium curtum (strain ATCC 700683 / DSM 15641 / CCUG 43107 /
OS 12-3).
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Cryptobacterium.
OX NCBI_TaxID=469378 {ECO:0000313|EMBL:ACU94651.1, ECO:0000313|Proteomes:UP000000954};
RN [1] {ECO:0000313|EMBL:ACU94651.1, ECO:0000313|Proteomes:UP000000954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700683 / DSM 15641 / 12-3
RC {ECO:0000313|Proteomes:UP000000954};
RX PubMed=21304644; DOI=10.40456/sigs.12260;
RA Mavrommatis K., Pukall R., Rohde C., Chen F., Sims D., Brettin T.,
RA Kuske C., Detter J.C., Han C., Lapidus A., Copeland A., Glavina Del Rio T.,
RA Nolan M., Lucas S., Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S.,
RA Ovchinnikova G., Pati A., Ivanova N., Chen A., Palaniappan K., Chain P.,
RA D'haeseleer P., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Rohde M., Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Cryptobacterium curtum type strain (12-3).";
RL Stand. Genomic Sci. 1:93-100(2009).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP001682; ACU94651.1; -; Genomic_DNA.
DR RefSeq; WP_012803337.1; NC_013170.1.
DR AlphaFoldDB; C7MP11; -.
DR STRING; 469378.Ccur_09550; -.
DR KEGG; ccu:Ccur_09550; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_2_11; -.
DR OrthoDB; 9789078at2; -.
DR Proteomes; UP000000954; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:ACU94651.1};
KW Cell division {ECO:0000313|EMBL:ACU94651.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000954};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 79..223
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 270..569
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 581 AA; 62013 MW; 87F6710C7D9D03A9 CRC64;
MASRPSSRYP RASSRVSHSH QFDETAALVP ASGSRVTFIL ILFALVALVG VFRLAYLSLI
IGPDNAAEAI ASRTQTVQVE AKRGTIYDRN GKVLATTIDA TTIYCNPSEV TDPEGDANLL
AGELGGTASD YIDALSKSDS SFAYIYRKAD KDTAVRIKDM KLAGIYFLAD SKRVYPYGQV
AGQVIGLCDV DGKGVSGLEL YYDETLAGTS GEMRIERGGN GYAVAGGLTE VRQAQDGKDI
VVSLDVDMQE RLETRLTKEV SELSGKRGDA LLYDGATGEV IACASTPYLN PEDRSSVKEG
STSLMPISVA YEPGSIFKGV TMAAILEAGV LSPESELYCP SSLPADEYTV TDAHDRASET
MTLTQILARS SNIGTSLAAK QLGFRQLYHK IQAYGLTEAT GIDFPGESAG YCTDVSTWST
IQSYNVSFGQ GLTVTPLQMA RFYGALANGG VAYQPHFLLS GNTPDSQNAS SWEEGQIFEN
TEALAPLEGM LQEVVAKGTG KKAQIEGFKP AGKTGTAQYT DDSGRYASDR YNISFIGYIP
ASTSKLVCFV GVTEVPGDAS TASAFKDIMS FAINRYKITA Q
//
