ID C7N4U2_SLAHD Unreviewed; 557 AA.
AC C7N4U2;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Cell division protein FtsI/penicillin-binding protein 2 {ECO:0000313|EMBL:ACV21927.1};
GN OrderedLocusNames=Shel_08800 {ECO:0000313|EMBL:ACV21927.1};
OS Slackia heliotrinireducens (strain ATCC 29202 / DSM 20476 / NCTC 11029 /
OS RHS 1) (Peptococcus heliotrinreducens).
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Slackia.
OX NCBI_TaxID=471855 {ECO:0000313|EMBL:ACV21927.1, ECO:0000313|Proteomes:UP000002026};
RN [1] {ECO:0000313|EMBL:ACV21927.1, ECO:0000313|Proteomes:UP000002026}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29202 / DSM 20476 / NCTC 11029 / RHS 1
RC {ECO:0000313|Proteomes:UP000002026};
RX PubMed=21304663; DOI=10.4056/sigs.37633;
RA Pukall R., Lapidus A., Nolan M., Copeland A., Glavina Del Rio T., Lucas S.,
RA Chen F., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L., Kuske C.,
RA Brettin T., Detter J.C., Han C., Pitluck S., Pati A., Mavrommatis K.,
RA Ivanova N., Ovchinnikova G., Chen A., Palaniappan K., Schneider S.,
RA Rohde M., Chain P., D'haeseleer P., Goker M., Bristow J., Eisen J.A.,
RA Markowitz V., Kyrpides N.C., Klenk H.P., Hugenholtz P.;
RT "Complete genome sequence of Slackia heliotrinireducens type strain (RHS
RT 1).";
RL Stand. Genomic Sci. 1:234-241(2009).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP001684; ACV21927.1; -; Genomic_DNA.
DR RefSeq; WP_012798031.1; NC_013165.1.
DR AlphaFoldDB; C7N4U2; -.
DR STRING; 471855.Shel_08800; -.
DR KEGG; shi:Shel_08800; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_0_11; -.
DR Proteomes; UP000002026; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:ACV21927.1};
KW Cell division {ECO:0000313|EMBL:ACV21927.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002026};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 57..202
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 245..545
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 557 AA; 60242 MW; 0CF2063491B145FA CRC64;
MPTIPGSRTL SGRVLIIFVA FLIAALALVG RLAYLQLIKA PEYASMAESS RTVNVTIPAK
RGTIYDRNGN VLATSVDATT IYCDPTMVDD PREMADALAE CLGGKSDDYL ALITQDTTFV
YVKRKADVNK AESLKEKGLS GLYFLPDSRR VYPYGSSAGQ IVGASNIDDV GITGLELYYD
DILSGVPGKM VYEQSATGIP IPNATVVERD AADGQDIIIS IDIDMQIYME ERLSQGVADM
GGSDGTAVLM DAATGEIYAI ASTPYFNPGD LSEVEDGATS IKAITSGLEP GSIFKTVSAT
AILENGKMTP DTEVFCPAYL AVDEYYIEDM HERGDMTMTF RDIIRDSSNV GISLSVDEYL
GYDKLYDKIL EYGLHSATGV DYPGEEVGFL SDYSEWSMTQ AYNISFGQGI TCTPLQMTRF
YGALRNDGVA VTPHFLVSLP QSGETPEYET EQIIQNTEAV PTMVDMLQTV VEEGTGVDAQ
MEGFTVVGKT GTAEFALETG GYSTTMSNRD FVGFLPNSTS SLVCYVGVDH VPVTGAVTPI
FRDIMTFAVD QYRIAEQ
//
