ID C7NYZ3_HALMD Unreviewed; 310 AA.
AC C7NYZ3;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Biotin/acetyl-CoA-carboxylase ligase {ECO:0000313|EMBL:ACV48682.1};
DE EC=6.3.4.15 {ECO:0000313|EMBL:ACV48682.1};
GN OrderedLocusNames=Hmuk_2576 {ECO:0000313|EMBL:ACV48682.1};
OS Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB
OS 13541) (Haloarcula mukohataei).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halomicrobium.
OX NCBI_TaxID=485914 {ECO:0000313|EMBL:ACV48682.1, ECO:0000313|Proteomes:UP000001746};
RN [1] {ECO:0000313|EMBL:ACV48682.1, ECO:0000313|Proteomes:UP000001746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541
RC {ECO:0000313|Proteomes:UP000001746};
RX PubMed=21304667; DOI=10.4056/sigs.42644;
RA Tindall B.J., Schneider S., Lapidus A., Copeland A., Glavina Del Rio T.,
RA Nolan M., Lucas S., Chen F., Tice H., Cheng J.F., Saunders E., Bruce D.,
RA Goodwin L., Pitluck S., Mikhailova N., Pati A., Ivanova N., Mavrommatis K.,
RA Chen A., Palaniappan K., Chain P., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Brettin T., Han C., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.,
RA Detter J.C.;
RT "Complete genome sequence of Halomicrobium mukohataei type strain (arg-
RT 2).";
RL Stand. Genomic Sci. 1:270-277(2009).
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DR EMBL; CP001688; ACV48682.1; -; Genomic_DNA.
DR RefSeq; WP_015763524.1; NC_013202.1.
DR AlphaFoldDB; C7NYZ3; -.
DR STRING; 485914.Hmuk_2576; -.
DR GeneID; 8412122; -.
DR KEGG; hmu:Hmuk_2576; -.
DR eggNOG; arCOG01940; Archaea.
DR HOGENOM; CLU_051096_0_0_2; -.
DR OrthoDB; 46252at2157; -.
DR Proteomes; UP000001746; Chromosome.
DR GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16442; BPL; 1.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 2.30.30.100; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_00978; Bifunct_BirA; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR030855; Bifunct_BirA.
DR InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR InterPro; IPR003142; BPL_C.
DR InterPro; IPR004143; BPL_LPL_catalytic.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00121; birA_ligase; 1.
DR PANTHER; PTHR12835; BIOTIN PROTEIN LIGASE; 1.
DR PANTHER; PTHR12835:SF5; BIOTIN--PROTEIN LIGASE; 1.
DR Pfam; PF02237; BPL_C; 1.
DR Pfam; PF03099; BPL_LplA_LipB; 1.
DR Pfam; PF08279; HTH_11; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ACV48682.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001746}.
FT DOMAIN 62..249
FT /note="BPL/LPL catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51733"
SQ SEQUENCE 310 AA; 32847 MW; 423BA4AD7C431F7D CRC64;
MQATREQVLD ALSEGPVAGP ALADRLDVSR AAVWKHVEQL RAEGFEIDSG DGGYELVSVP
EFGASAVAYG LEAPFEIEYH DSIDSTNRRA RELATDGRSD VAVLADEQTG GRGRLDRAWA
SPSGGVWLSL ALRPGVPIAH APAFTLAAAV AVTRAAREAG VDARIKWPND VVVGDDERKL
AGVLTEVEGE ADRVDWVVVG IGSNVNVDPA ALPDEADATS VQDAVGPVDR RAFTQRLLEE
FDALRRDLDA VVPAWRADAT TLGKRVRVET PGGTVEGEAV DVSFPGALVV DTGEERVTIT
AGDCEHLRPA
//
