ID C7P112_HALMD Unreviewed; 657 AA.
AC C7P112;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Glycoside hydrolase family 18 {ECO:0000313|EMBL:ACV49027.1};
GN OrderedLocusNames=Hmuk_2922 {ECO:0000313|EMBL:ACV49027.1};
OS Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB
OS 13541) (Haloarcula mukohataei).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halomicrobium.
OX NCBI_TaxID=485914 {ECO:0000313|EMBL:ACV49027.1, ECO:0000313|Proteomes:UP000001746};
RN [1] {ECO:0000313|EMBL:ACV49027.1, ECO:0000313|Proteomes:UP000001746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541
RC {ECO:0000313|Proteomes:UP000001746};
RX PubMed=21304667; DOI=10.4056/sigs.42644;
RA Tindall B.J., Schneider S., Lapidus A., Copeland A., Glavina Del Rio T.,
RA Nolan M., Lucas S., Chen F., Tice H., Cheng J.F., Saunders E., Bruce D.,
RA Goodwin L., Pitluck S., Mikhailova N., Pati A., Ivanova N., Mavrommatis K.,
RA Chen A., Palaniappan K., Chain P., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Brettin T., Han C., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.,
RA Detter J.C.;
RT "Complete genome sequence of Halomicrobium mukohataei type strain (arg-
RT 2).";
RL Stand. Genomic Sci. 1:270-277(2009).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC class II subfamily. {ECO:0000256|ARBA:ARBA00009121}.
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DR EMBL; CP001688; ACV49027.1; -; Genomic_DNA.
DR RefSeq; WP_015763869.1; NC_013202.1.
DR AlphaFoldDB; C7P112; -.
DR STRING; 485914.Hmuk_2922; -.
DR CAZy; CBM5; Carbohydrate-Binding Module Family 5.
DR CAZy; GH18; Glycoside Hydrolase Family 18.
DR GeneID; 8412474; -.
DR KEGG; hmu:Hmuk_2922; -.
DR eggNOG; arCOG07581; Archaea.
DR HOGENOM; CLU_002833_14_4_2; -.
DR OrthoDB; 8638at2157; -.
DR Proteomes; UP000001746; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd12215; ChiC_BD; 2.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 2.10.10.20; Carbohydrate-binding module superfamily 5/12; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR003610; CBM_fam5/12.
DR InterPro; IPR036573; CBM_sf_5/12.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR11177; CHITINASE; 1.
DR PANTHER; PTHR11177:SF317; CHITINASE 11; 1.
DR Pfam; PF02839; CBM_5_12; 2.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR Pfam; PF18911; PKD_4; 1.
DR SMART; SM00495; ChtBD3; 2.
DR SMART; SM00636; Glyco_18; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF51055; Carbohydrate binding domain; 2.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
DR PROSITE; PS50093; PKD; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ACV49027.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001746}.
FT DOMAIN 153..231
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 242..657
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT REGION 69..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 521..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 657 AA; 71617 MW; 28ACE264D3DDE5AB CRC64;
MQRRNYLQSL SALAGLAGVS AVTAQEEYPA YDSSATYNGG DRVVYEGYIW EAQWWTKGTA
PSADKAVWEK VGPADGGGGD DGGSDDGGSS DIPAYDSSAT YTGGDQVTYD GFVWEAEWWT
KGTEPSESAN VWTKVRAVDD GDNGGDDGGS SDLNAVIDAS ATRVDVGEDV TLDASGSEGD
IESYEWMVGD QGPISGVENT VTLDEEGTYE VTLTVTDADG NEATATRSVF VGTAGGTQPG
DKRVVAYYRQ WAQYDREYTP SDMPLDNITH VQYAFARPEE DGSVNLVGDS HGQQAFWDQN
TDWRDAPGGK SIAELAEENE DTKFTLSIGG WGDSEYFSYA AETEENRQRF ADQCAEWVDR
GNLDGIDIDW EFPHGGGCQG DGGEACNKEN VERPEIDIPN FTKLCQAVRD RLDEKAAEEG
REEPYEVTAA VNADPEAMAD YEHEALSDIL DFILVMTFDY AGIWSEYTRH HAPLKENPDN
PFEKSDSWNA SYALSWFEQQ GWSPDQLNMA VPFYGRSWSN VNDPDGEGNG EDDGLFQKFD
GEDGNASGDG SFGTIGGIYE YYDLAGGSRG GSSIIDGDDY ETYIDEDAMT AYSYNPDKGG
GYNKASGEMI SHDTVETMEM KAQWLRDSPY GGTMLWAIGG DTKDGELIST LWNTLNE
//
