ID C7P201_HALMD Unreviewed; 250 AA.
AC C7P201;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Uroporphyrinogen III synthase HEM4 {ECO:0000313|EMBL:ACV47230.1};
GN OrderedLocusNames=Hmuk_1103 {ECO:0000313|EMBL:ACV47230.1};
OS Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB
OS 13541) (Haloarcula mukohataei).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halomicrobium.
OX NCBI_TaxID=485914 {ECO:0000313|EMBL:ACV47230.1, ECO:0000313|Proteomes:UP000001746};
RN [1] {ECO:0000313|EMBL:ACV47230.1, ECO:0000313|Proteomes:UP000001746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541
RC {ECO:0000313|Proteomes:UP000001746};
RX PubMed=21304667; DOI=10.4056/sigs.42644;
RA Tindall B.J., Schneider S., Lapidus A., Copeland A., Glavina Del Rio T.,
RA Nolan M., Lucas S., Chen F., Tice H., Cheng J.F., Saunders E., Bruce D.,
RA Goodwin L., Pitluck S., Mikhailova N., Pati A., Ivanova N., Mavrommatis K.,
RA Chen A., Palaniappan K., Chain P., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Brettin T., Han C., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.,
RA Detter J.C.;
RT "Complete genome sequence of Halomicrobium mukohataei type strain (arg-
RT 2).";
RL Stand. Genomic Sci. 1:270-277(2009).
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DR EMBL; CP001688; ACV47230.1; -; Genomic_DNA.
DR RefSeq; WP_015762076.1; NC_013202.1.
DR AlphaFoldDB; C7P201; -.
DR STRING; 485914.Hmuk_1103; -.
DR GeneID; 8410622; -.
DR KEGG; hmu:Hmuk_1103; -.
DR eggNOG; arCOG02048; Archaea.
DR HOGENOM; CLU_011276_9_5_2; -.
DR OrthoDB; 15395at2157; -.
DR Proteomes; UP000001746; Chromosome.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR039793; UROS/Hem4.
DR PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR Pfam; PF02602; HEM4; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001746}.
FT DOMAIN 22..236
FT /note="Tetrapyrrole biosynthesis uroporphyrinogen III
FT synthase"
FT /evidence="ECO:0000259|Pfam:PF02602"
SQ SEQUENCE 250 AA; 25887 MW; 7CAB9217EAF6C4A0 CRC64;
MREEPRLSVA VFRPDDERTT QAVELLESLG ADPVPDPMLA VEATGATPRS DADYVVLTSK
TGVELATEAG WDPGDATVCA IGRPTADVLE DAGYAVDLVP EEYSSTGLVA ALEESVDGAR
VEVARSDHGS AVLTDGLEAA GAYVHETILY RLVRPEGAGA STERAAAGDL DAALFTSSLT
VRHFLAAADE RGIRADAVEG LNDAVVGAIG EPTRQTATDA GIDVDVVPDT ADFETLATTA
VEAAAPSHRE
//
