ID C7PYB5_CATAD Unreviewed; 735 AA.
AC C7PYB5;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=MMPL domain protein {ECO:0000313|EMBL:ACU75405.1};
DE Flags: Precursor;
GN OrderedLocusNames=Caci_6559 {ECO:0000313|EMBL:ACU75405.1};
OS Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL
OS B-24433 / ID139908).
OC Bacteria; Actinomycetota; Actinomycetes; Catenulisporales;
OC Catenulisporaceae; Catenulispora.
OX NCBI_TaxID=479433 {ECO:0000313|EMBL:ACU75405.1, ECO:0000313|Proteomes:UP000000851};
RN [1] {ECO:0000313|EMBL:ACU75405.1, ECO:0000313|Proteomes:UP000000851}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908
RC {ECO:0000313|Proteomes:UP000000851};
RX PubMed=21304647; DOI=10.4056/sigs.17259;
RA Copeland A., Lapidus A., Glavina Del Rio T., Nolan M., Lucas S., Chen F.,
RA Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Mikhailova N.,
RA Pati A., Ivanova N., Mavromatis K., Chen A., Palaniappan K., Chain P.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.D., Chertkov O., Brettin T.,
RA Detter J.C., Han C., Ali Z., Tindall B.J., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Catenulispora acidiphila type strain (ID
RT 139908).";
RL Stand. Genomic Sci. 1:119-125(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP001700; ACU75405.1; -; Genomic_DNA.
DR AlphaFoldDB; C7PYB5; -.
DR STRING; 479433.Caci_6559; -.
DR KEGG; cai:Caci_6559; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_1_1_11; -.
DR InParanoid; C7PYB5; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000000851; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000851};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 178..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 549..570
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 590..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 638..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 664..683
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 194..327
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 713..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 735 AA; 76913 MW; 2CDF61F5D353B091 CRC64;
MAGIARWCFR HRFLVPVLWL VALVGLGVVG SALGSNYANS FSLPGTESTK ALTILQTQFA
SQSGDQDTVV WRTTSGTVRD AQVQGSMTAA LDKIAKLPEV AAVRGPYGPQ GAAQQISKDG
TTAYAQINFT GQANELVDAD VKAVINTAQA AATPTLQVEL TGNAIDQVSE AKPSSSEAYG
IAAAAVVLFI AFGSLFAMLL PILTAVFGLG AGILAVNLLT HAFSIAQLAP TLSALIGLGV
GIDYALFIVT RYRRGLKRGL APEDAVAIAL DTSGRAVLFA GGTVCIALLG MLVLGISFLN
GVAVAAALTV VFTVLSALTL LPALLGILGT RVLSRKQRRL LAANGPESEE LQGFWARWAG
FVERRPKILS VVALAVLVTL VIPVGSLRLG HSDDGNAPTS STSRKAYDLL ASGFGPGFNG
PLEIVGTFTS PADEAAFTSL AKTLATVPNV AAVQAPPLKP GATIGLMQVY PRTNPDAVQT
TDLIAHLRST VIPAARAGTT MSVYITGGTA IFYDFAHVLD GKLPLFIGVI IGLGFLLLLV
AFRSFGVPAM AAVMNLLGAG ASFGVLVAIF QWGWGLNAMG LGTSGPIEAF LPVMMLSILF
GLSMDYQVFL VSRMHEEWVH SEDNQRAVRI GQAETGRVIT AAAAIMISVF MAFVFGGQRV
IAEFGIGLAA AVAIDAFIIR TVLVPSAMQV LGRANWWLPT WLDKRLPHLS VDPPEERVTL
PQQGQADDSV PSAAL
//
