ID C8C417_PIG Unreviewed; 501 AA.
AC C8C417; F1RRY3;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Calcium-binding mitochondrial carrier protein SCaMC-2 isoform b {ECO:0000313|EMBL:HDB38826.1};
DE SubName: Full=Solute carrier family 25 member 25 {ECO:0000313|EMBL:ACU44650.1};
GN Name=SLC25A25 {ECO:0000313|EMBL:ACU44650.1};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|EMBL:ACU44650.1};
RN [1] {ECO:0000313|EMBL:ACU44650.1}
RP NUCLEOTIDE SEQUENCE.
RA Liu G.Y.;
RL Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:HDB38826.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=30723633; DOI=.7717/peerj.6374;
RA Gilbert D.G.;
RT "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.";
RL PeerJ 7:E6374-E6374(2019).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; GQ368239; ACU44650.1; -; mRNA.
DR EMBL; DQIR01183349; HDB38826.1; -; Transcribed_RNA.
DR RefSeq; NP_001157982.1; NM_001164510.1.
DR GeneID; 100156347; -.
DR KEGG; ssc:100156347; -.
DR CTD; 114789; -.
DR HOGENOM; CLU_015166_2_0_1; -.
DR OrthoDB; 1330359at2759; -.
DR TreeFam; TF313492; -.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR002167; GDC-like.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR24089:SF769; CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN SCAMC-2; 1.
DR PANTHER; PTHR24089; SOLUTE CARRIER FAMILY 25; 1.
DR Pfam; PF13499; EF-hand_7; 2.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00928; GRAVESDC.
DR PRINTS; PR00926; MITOCARRIER.
DR SMART; SM00054; EFh; 4.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50222; EF_HAND_2; 3.
DR PROSITE; PS50920; SOLCAR; 3.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT DOMAIN 43..78
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 110..145
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 146..181
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REPEAT 216..302
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 310..395
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 407..495
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 501 AA; 55173 MW; A52EFC3764EE06F6 CRC64;
MVSSVLCRCV ASPPPDAAAT ASSSASSPAS VDPCGGAVCG GPDHQLRLWS LFQTLDVNRD
GGLCVNDLAV GLRRLGLHRT EGELQKIVQA GDKDLDGQLD FEEFVHYLQD HEKKLRLVFK
SLDKKNDGRI DAQEIMQSLR DLGVKISEQQ AEKILKSMDK NGTMTIDWNE WRDYHLLHPV
ENIPEIILYW KHSTIFDVGE NLTVPDEFTV EERQTGMWWR HLVAGGGAGA VSRTCTAPLD
RLKVLMQVHA SRSNNMCIVG GFTQMIREGG ARSLWRGNGI NVLKIAPESA IKFMAYEQIK
RLVGTDQETL RIHERLVAGS LAGAIAQSSI YPMEVLKTRM ALRKTGQYSG MLDCARKILA
REGVAAFYKG YVPNMLGIIP YAGIDLAVYE TLKNAWLQRY AVNSADPGVF VLLACGTMSS
TCGQLASYPL ALVRTRMQAQ ASVEGAPEVS MSSLFKQILR TEGAFGLYRG LAPNFMKVIP
AVSISYVVYE NLKITLGVQS R
//
