ID C8N8X2_CARH6 Unreviewed; 400 AA.
AC C8N8X2;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Beta-ketoacyl synthase, C-terminal domain protein {ECO:0000313|EMBL:EEV88958.1};
DE EC=2.3.1.41 {ECO:0000313|EMBL:EEV88958.1};
GN ORFNames=HMPREF0198_0950 {ECO:0000313|EMBL:EEV88958.1};
OS Cardiobacterium hominis (strain ATCC 15826 / DSM 8339 / NCTC 10426 / 6573).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cardiobacteriales;
OC Cardiobacteriaceae; Cardiobacterium.
OX NCBI_TaxID=638300 {ECO:0000313|EMBL:EEV88958.1, ECO:0000313|Proteomes:UP000004870};
RN [1] {ECO:0000313|EMBL:EEV88958.1, ECO:0000313|Proteomes:UP000004870}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15826 / DSM 8339 / NCTC 10426 / 6573
RC {ECO:0000313|Proteomes:UP000004870};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEV88958.1}.
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DR EMBL; ACKY01000046; EEV88958.1; -; Genomic_DNA.
DR RefSeq; WP_004140539.1; NZ_GG694026.1.
DR AlphaFoldDB; C8N8X2; -.
DR STRING; 2718.CHUV0807_1247; -.
DR GeneID; 84788894; -.
DR HOGENOM; CLU_000022_69_0_6; -.
DR OrthoDB; 5559162at2; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000004870; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF320; BETA-KETOACYL SYNTHASE; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:EEV88958.1};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Reference proteome {ECO:0000313|Proteomes:UP000004870};
KW Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:EEV88958.1}.
FT DOMAIN 1..394
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 400 AA; 41047 MW; B444140C07BED59A CRC64;
MTVYLHRPGL VSALGSGAAS FTAACAPEIP RLQYEEGWLR GRRIAVGRYH GDGLSPPPLP
PDYRSHNNTL LWQALAQIED TIHAALARYG AERVAVILGT STSGGDDNRS ALQACLDGAP
LATTGFSVPR QLMSAPADFT AAVFGTRGLC YGISTACTSG ARALISAARL LRSGAADAVI
CGGVDTLSLL TLHGFAALEV LSSGIARPFS AARDGINMGE AAAVFVATRE ALHDDALCLL
GYGASSDAWH MSSPRPDGAG AIAAMQAALT QAAVAPQAVG WLNLHGTGTP QNDQMEALAV
ATVLPQVACT STKPLTGHTL AAAGALEAAL CWLAVSRRDN PGGRLPPMAV HDYDPALAPI
HLTDTAAHWP DGRRIAMSTS FAFGGSNAAL VIGEADANAA
//
