ID C8NDK3_CARH6 Unreviewed; 754 AA.
AC C8NDK3;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Glycosyl hydrolase family 65 central catalytic domain protein {ECO:0000313|EMBL:EEV87304.1};
DE EC=2.4.1.8 {ECO:0000313|EMBL:EEV87304.1};
GN Name=map2 {ECO:0000313|EMBL:EEV87304.1};
GN ORFNames=HMPREF0198_2581 {ECO:0000313|EMBL:EEV87304.1};
OS Cardiobacterium hominis (strain ATCC 15826 / DSM 8339 / NCTC 10426 / 6573).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cardiobacteriales;
OC Cardiobacteriaceae; Cardiobacterium.
OX NCBI_TaxID=638300 {ECO:0000313|EMBL:EEV87304.1, ECO:0000313|Proteomes:UP000004870};
RN [1] {ECO:0000313|EMBL:EEV87304.1, ECO:0000313|Proteomes:UP000004870}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15826 / DSM 8339 / NCTC 10426 / 6573
RC {ECO:0000313|Proteomes:UP000004870};
RA Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 65 family.
CC {ECO:0000256|ARBA:ARBA00006768}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEV87304.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACKY01000142; EEV87304.1; -; Genomic_DNA.
DR RefSeq; WP_004143546.1; NZ_GG694032.1.
DR AlphaFoldDB; C8NDK3; -.
DR STRING; 2718.CHUV0807_2298; -.
DR GeneID; 84790801; -.
DR HOGENOM; CLU_006285_2_2_6; -.
DR OrthoDB; 9816160at2; -.
DR Proteomes; UP000004870; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0050082; F:maltose phosphorylase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.70.98.40; Glycoside hydrolase, family 65, N-terminal domain; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR005194; Glyco_hydro_65_C.
DR InterPro; IPR005195; Glyco_hydro_65_M.
DR InterPro; IPR005196; Glyco_hydro_65_N.
DR InterPro; IPR037018; Glyco_hydro_65_N_sf.
DR InterPro; IPR017045; Malt_Pase/Glycosyl_Hdrlase.
DR PANTHER; PTHR11051; GLYCOSYL HYDROLASE-RELATED; 1.
DR PANTHER; PTHR11051:SF14; MALTOSE PHOSPHORYLASE; 1.
DR Pfam; PF03633; Glyco_hydro_65C; 1.
DR Pfam; PF03632; Glyco_hydro_65m; 1.
DR Pfam; PF03636; Glyco_hydro_65N; 1.
DR PIRSF; PIRSF036289; Glycosyl_hydrolase_malt_phosph; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000313|EMBL:EEV87304.1};
KW Hydrolase {ECO:0000313|EMBL:EEV87304.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004870};
KW Transferase {ECO:0000313|EMBL:EEV87304.1}.
FT DOMAIN 15..261
FT /note="Glycoside hydrolase family 65 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03636"
FT DOMAIN 318..671
FT /note="Glycoside hydrolase family 65 central catalytic"
FT /evidence="ECO:0000259|Pfam:PF03632"
FT DOMAIN 681..742
FT /note="Glycoside hydrolase family 65 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03633"
FT ACT_SITE 482
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-50"
FT BINDING 353..354
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
FT BINDING 584..585
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
SQ SEQUENCE 754 AA; 85773 MW; AF087EEF8B5C96D6 CRC64;
MYLRIMEIHP WSIRSTKLEK EHKRLQESLT SLGNGYMGMR GNFEETYSGD SHLGTYIGGV
WFPDKTRVGW WKNGYPKYFG KAINALNYSK VAIYVDGQEV DLGKHAPTDF VLELDMHTGV
LHRQFTLFGV QFRISKFLSV AQKELALIRW DITATDGKTH KVRIDAVIDA DVKNEDANYE
EKFWQVLARD VAADRGSIAT QTVANPFGVD QFIVNAEQTF AGDFTATGHD SSDWRVTNRF
EAEVGAAPKT FEKRVIITTS RDYDGLAAVQ KAGRDLSANI SGQNHADLLA AHEAGWKQRW
DIADVVISGN NEAQQGIRFN LFQLFATYYG EDARLNIGPK GFTGEKYGGA TYWDTEAYAV
PLYLALAEPN VTRNLLKYRH NQLPQAQHNA RQQGLAGALY PMVTFTGVEC HNEWEITFEE
IHRNGAIPYA IYNYTNYTGD DSYLAKEGLE VLVEVSRFWA DRVHYSKRHG KYMIHGVTGP
NEYENNINNN WYTNTLAAWV LQYTLEALQK HPRPDLNISD AERGKWQDII ANMYYPEDKE
QGIFVQHDGF LDKDIRPVSA LSPDDLPLNQ KWSWDKILRS PFIKQADVLQ GIYFFGDRYT
LDEKRRNFDY YEPMTVHESS LSPSIHAILA AELGKEAKAV EMYQRTARLD LDNYNNDTED
GLHITSMTGS WLAIVQGFAQ MKTWGGTLSF APFLPSDWTG YTFHINYRGR LIKIEVDGKN
VTLRLLKGDA LPLKLYGETL TLKDSHSAPL QKNG
//
