ID C8S365_9RHOB Unreviewed; 975 AA.
AC C8S365;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 24-JAN-2024, entry version 61.
DE SubName: Full=Sarcosine oxidase, alpha subunit family {ECO:0000313|EMBL:EEW24547.1};
GN ORFNames=Rsw2DRAFT_2493 {ECO:0000313|EMBL:EEW24547.1};
OS Rhodobacter sp. SW2.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Rhodobacter.
OX NCBI_TaxID=371731 {ECO:0000313|EMBL:EEW24547.1, ECO:0000313|Proteomes:UP000010121};
RN [1] {ECO:0000313|EMBL:EEW24547.1, ECO:0000313|Proteomes:UP000010121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SW2 {ECO:0000313|EMBL:EEW24547.1,
RC ECO:0000313|Proteomes:UP000010121};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Larimer F., Land M.L., Hauser L., Emerson D.;
RT "The draft genome of Rhodobacter sp. SW2.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEW24547.1}.
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DR EMBL; ACYY01000017; EEW24547.1; -; Genomic_DNA.
DR RefSeq; WP_008031493.1; NZ_ACYY01000017.1.
DR AlphaFoldDB; C8S365; -.
DR STRING; 371731.Rsw2DRAFT_2493; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0446; Bacteria.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000010121; Unassembled WGS sequence.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF12831; FAD_oxidored; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000010121}.
FT DOMAIN 498..582
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 597..856
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 882..967
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 975 AA; 104224 MW; 517FDC8A3BC7D968 CRC64;
MRIDGKGLID RGSPVRFRFD GVEYDGFRGD TLASALLANG VKLVGRSFKY HRPRGVLTAG
SEEPNALVEV IERGQQTPNV RATVQEVYDG LQARSQNRWP SLKYDLLAVN DLAAPFLSAG
FYYKTFMWPR SFWEKLYEPM IRRAAGLGRL SGRHDQAVYE KAFAFCDLLV IGAGPTGLQA
ALTAARAGAD VILADEDARM GGRLLSELEA IDGSPALEWV AAVLAELAAL PNVRLMPRTT
VTGAYDGGTY GALERVGLHL PEAADRPREC FWRIVAGQAV LAAGALERPI AFEDNDRPGI
LLASAVRSYV NRYGVAPGSR VAVFGNNDDA RRTARDLMAA GIRVAALIDS RAGVSTDEDF
PVYAGAVVSG TRGRLALDEI TVQHANGTVQ IAADCLAISG GWNPTLHLTC HMNGRPIWND
DLASFVPSRG AVPGLTAAGA ANGAFGTAAC LAEGQAAALA ALQALGRVAK PAPLPVAEDF
GYGLQPLWAV PGSGKAHGRA WLDFANDVTV KDVKLAAVEN YASVEHMKRY TTQGMAPDQG
KNSNIGALAV LADATGRGIP ETGTTTYRPP FVPVPIAAMG AGGRGKGFAP QRLMTSHSAS
VALGAPMIEA GLWYRPSYFP RPGEATWREA CDREVRMVRQ VVGVCDVSTL GKIDIQGADA
ARFLDLVYTN TFSSLPVGRV RYGLMLREDG HVLDDGTTAR LGDSHFLMTT TTAAAGLVMR
HLDFIQQAFC ADWDLRTISV TESWAQFAIA GPKARDLLAA VMDGPVVLPF MGCMDVQEQG
VAARLFRISF SGEEGYEIAV PARYGEALFR DLLARAEVMG GGPYGMEALN VLRIEKGFIT
HAEIHGRTTA FDIGMEKMVA AKDCIGKAAA RRPGLVGPAR EQLVGLKPLA DAPLTAGAHL
YAPGAAASRD NDQGYVTSVC YSPTLESWLA LAFLKDGRAR LGESIRLVDP LRQIDVICTV
CDPVFHDKEG KKLRA
//
