ID MDJ1_EMENI Reviewed; 547 AA.
AC C8V213; Q5AZT6; Q6XPR4;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=DnaJ homolog 1, mitochondrial;
DE Flags: Precursor;
GN ORFNames=AN10778;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAA57980.1; Type=Erroneous gene model prediction; Note=The predicted gene AN6194 has been split into 2 genes: AN10778 and AN10788.; Evidence={ECO:0000305};
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DR EMBL; AACD01000105; EAA57980.1; ALT_SEQ; Genomic_DNA.
DR EMBL; BN001301; CBF69996.1; -; Genomic_DNA.
DR RefSeq; XP_663798.1; XM_658706.1.
DR AlphaFoldDB; C8V213; -.
DR SMR; C8V213; -.
DR STRING; 227321.C8V213; -.
DR EnsemblFungi; CBF69996; CBF69996; ANIA_10778.
DR GeneID; 2870728; -.
DR KEGG; ani:AN6194.2; -.
DR eggNOG; KOG0715; Eukaryota.
DR HOGENOM; CLU_003661_1_0_1; -.
DR InParanoid; C8V213; -.
DR OMA; CPECAGD; -.
DR OrthoDB; 24567at2759; -.
DR Proteomes; UP000000560; Chromosome I.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0031072; F:heat shock protein binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR GO; GO:0051085; P:chaperone cofactor-dependent protein refolding; IBA:GO_Central.
DR GO; GO:0042026; P:protein refolding; IBA:GO_Central.
DR GO; GO:0009408; P:response to heat; IEA:InterPro.
DR CDD; cd06257; DnaJ; 1.
DR CDD; cd10747; DnaJ_C; 1.
DR CDD; cd10719; DnaJ_zf; 1.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR Gene3D; 2.10.230.10; Heat shock protein DnaJ, cysteine-rich domain; 1.
DR Gene3D; 2.60.260.20; Urease metallochaperone UreE, N-terminal domain; 2.
DR HAMAP; MF_01152; DnaJ; 1.
DR InterPro; IPR012724; DnaJ.
DR InterPro; IPR002939; DnaJ_C.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR008971; HSP40/DnaJ_pept-bd.
DR InterPro; IPR001305; HSP_DnaJ_Cys-rich_dom.
DR InterPro; IPR036410; HSP_DnaJ_Cys-rich_dom_sf.
DR InterPro; IPR036869; J_dom_sf.
DR PANTHER; PTHR43096; DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43096:SF52; DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF01556; DnaJ_C; 1.
DR Pfam; PF00684; DnaJ_CXXCXGXG; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF57938; DnaJ/Hsp40 cysteine-rich domain; 1.
DR SUPFAM; SSF49493; HSP40/DnaJ peptide-binding domain; 2.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
DR PROSITE; PS51188; ZF_CR; 1.
PE 3: Inferred from homology;
KW Chaperone; Metal-binding; Mitochondrion; Reference proteome; Repeat;
KW Transit peptide; Zinc; Zinc-finger.
FT TRANSIT 1..79
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 80..547
FT /note="DnaJ homolog 1, mitochondrial"
FT /id="PRO_0000413169"
FT DOMAIN 83..147
FT /note="J"
FT REPEAT 253..260
FT /note="CXXCXGXG motif"
FT REPEAT 270..277
FT /note="CXXCXGXG motif"
FT REPEAT 293..300
FT /note="CXXCXGXG motif"
FT REPEAT 309..316
FT /note="CXXCXGXG motif"
FT ZN_FING 240..321
FT /note="CR-type"
FT REGION 484..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..539
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 547 AA; 57632 MW; 622E0C8E49EECCC9 CRC64;
MNPSSALMPK ATAIPGCILR TSRQCSKHNQ TSGIRASSST RQYHVAAIES PARRRRDSTF
MKRSDFIQAR NFHATKVLAA IPDPYKVLGV DKGASAGDIK KAYYGMAKKY HPDTNKDPGA
KEKFAEAQSA YELLSDKKKR ETYDRFGSAA FDQNGGFDPS AGAGGNPFAG GGGFHGFGGG
FGGGFPGGFA ADINIEDLFG AFAGGARRSG RGRRGPFQEI LVGEDIEVQT NISFMEAAKG
TSQDIVITPL KECGTCKGDG LKEGAKRTQC RQCNGTGTRV HLMQGGFQVA ATCDACGGAG
LIVPRGSHCG TCKGDGVVRE RKTVRVDIPG GVEDGMRLRI SGEGDAPPTG TAAAPGTRTQ
RGDLYVSIRV SPDERFSRSG SDILYTASIP LTTALLGGEV LVPTLDGQVK VKVATGTGTG
DRITLSGMGM KKLGGRSRGF SPNGDLKVEF KVAMPKYLTS NQRTILEVLA DEMGDKTARR
IMDIPRDGLS TAPAADASSG NESKSEGFLK SAWHKLMNHK KPAGSENSSD SSSNKDSNSS
GDSKKSE
//
