ID C8W691_DESAS Unreviewed; 207 AA.
AC C8W691;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Precorrin-8X methylmutase {ECO:0000313|EMBL:ACV62180.1};
DE EC=5.4.99.61 {ECO:0000313|EMBL:ACV62180.1};
GN OrderedLocusNames=Dtox_1298 {ECO:0000313|EMBL:ACV62180.1};
OS Desulfofarcimen acetoxidans (strain ATCC 49208 / DSM 771 / KCTC 5769 / VKM
OS B-1644 / 5575) (Desulfotomaculum acetoxidans).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulfofarcimen.
OX NCBI_TaxID=485916 {ECO:0000313|EMBL:ACV62180.1, ECO:0000313|Proteomes:UP000002217};
RN [1] {ECO:0000313|EMBL:ACV62180.1, ECO:0000313|Proteomes:UP000002217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49208 / DSM 771 / VKM B-1644
RC {ECO:0000313|Proteomes:UP000002217};
RX PubMed=21304664; DOI=10.4056/sigs.39508;
RA Spring S., Lapidus A., Schroder M., Gleim D., Sims D., Meincke L.,
RA Glavina Del Rio T., Tice H., Copeland A., Cheng J.F., Lucas S., Chen F.,
RA Nolan M., Bruce D., Goodwin L., Pitluck S., Ivanova N., Mavromatis K.,
RA Mikhailova N., Pati A., Chen A., Palaniappan K., Land M., Hauser L.,
RA Chang Y.J., Jeffries C.D., Chain P., Saunders E., Brettin T., Detter J.C.,
RA Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P., Han C.;
RT "Complete genome sequence of Desulfotomaculum acetoxidans type strain
RT (5575).";
RL Stand. Genomic Sci. 1:242-253(2009).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
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DR EMBL; CP001720; ACV62180.1; -; Genomic_DNA.
DR AlphaFoldDB; C8W691; -.
DR STRING; 485916.Dtox_1298; -.
DR KEGG; dae:Dtox_1298; -.
DR eggNOG; COG2082; Bacteria.
DR HOGENOM; CLU_084703_1_1_9; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000002217; Chromosome.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:UniProtKB-EC.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ACV62180.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002217}.
FT DOMAIN 10..206
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 207 AA; 22248 MW; CE32E65CE8660035 CRC64;
MHPVITNPRE IEKNSMQIIE DNVPELHKLP REHKEIIKRV IHTTGDLTFV NLVYIHPEAV
ASGLTALRAG RPIVTDINML KTGINKNRLQ ELGITAYCYI AEPRVIEESK KTGLTRAMIA
MKLAAAEAKD GIIAIGNAPT ALFTLCDLIK SGAAKPSLVI GTPVGFVGAK ESKDLLMQMD
IPHIAVPGTK GGSTIAAAIV NALLYLA
//
