ID C8X3N7_DESRD Unreviewed; 786 AA.
AC C8X3N7;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Transketolase domain protein {ECO:0000313|EMBL:ACV69034.1};
GN OrderedLocusNames=Dret_1750 {ECO:0000313|EMBL:ACV69034.1};
OS Desulfohalobium retbaense (strain ATCC 49708 / DSM 5692 / JCM 16813 /
OS HR100).
OC Bacteria; Thermodesulfobacteriota; Desulfovibrionia; Desulfovibrionales;
OC Desulfohalobiaceae; Desulfohalobium.
OX NCBI_TaxID=485915 {ECO:0000313|EMBL:ACV69034.1, ECO:0000313|Proteomes:UP000001052};
RN [1] {ECO:0000313|Proteomes:UP000001052}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5692 {ECO:0000313|Proteomes:UP000001052};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Mikhailova N., Munk A.C., Brettin T., Detter J.C., Han C., Tapia R.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Spring S., Klenk H.-P., Eisen J.A.;
RT "The complete chromosome of Desulfohalobium retbaense DSM 5692.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACV69034.1, ECO:0000313|Proteomes:UP000001052}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5692 {ECO:0000313|EMBL:ACV69034.1,
RC ECO:0000313|Proteomes:UP000001052};
RX PubMed=21304676;
RA Spring S., Nolan M., Lapidus A., Glavina Del Rio T., Copeland A., Tice H.,
RA Cheng J.F., Lucas S., Land M., Chen F., Bruce D., Goodwin L., Pitluck S.,
RA Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA Hauser L., Chang Y.J., Jeffries C.D., Munk C., Kiss H., Chain P., Han C.,
RA Brettin T., Detter J.C., Schuler E., Goker M., Rohde M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Desulfohalobium retbaense type strain
RT (HR(100)).";
RL Stand. Genomic Sci. 2:38-48(2010).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the transketolase family.
CC {ECO:0000256|ARBA:ARBA00007131}.
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DR EMBL; CP001734; ACV69034.1; -; Genomic_DNA.
DR RefSeq; WP_015752177.1; NC_013223.1.
DR AlphaFoldDB; C8X3N7; -.
DR STRING; 485915.Dret_1750; -.
DR KEGG; drt:Dret_1750; -.
DR eggNOG; COG0021; Bacteria.
DR HOGENOM; CLU_363588_0_0_7; -.
DR OrthoDB; 8732661at2; -.
DR Proteomes; UP000001052; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR005474; Transketolase_N.
DR PANTHER; PTHR43825; PYRUVATE DEHYDROGENASE E1 COMPONENT; 1.
DR PANTHER; PTHR43825:SF1; TRANSKETOLASE-LIKE PYRIMIDINE-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF00456; Transketolase_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001052}.
FT DOMAIN 144..318
FT /note="Transketolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00456"
FT DOMAIN 442..621
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|Pfam:PF02779"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 786 AA; 84041 MW; A52AAE6C086B3183 CRC64;
MGCTWGPRRG QWLDGEDIPS TTGLTSDERA YLEHFDAVYR ALCAMLYNYV PTSGHPGGSI
SCGRFVANLI WNHMDYDLGA PDEAAADQIV FAAGHKALGL YAMWALRDEI AAQYAPGILP
ELWQQRLRLE DLLGFRRNPA SMTPLRHRFQ AKSLDGHPTP ATPFVPLATG ASGVGLCGAI
GLALGFKDYY GDNAPRVHVV EGEGGLTPGR VSEALASAGT AGLDNLVLHL DWNQSSIDVD
RVCRDAAGPG QYVQWEPAEL LRLHDWNVIC VEDGTDWSGI DRAQAKALSF SNGQPTAIVY
RTTKGWQYGI EGRKSHGAGH ALCSTSFYEL LEPVLQELHG NLPSCSAAEV PACASADGDE
IREACFWQAL EQVRSLLGEA PACCRWLAGG VQQARERLLE QGRQSRFSSP PNVEAIGQAA
GRLGSTVPSD MAVAPNSSET LRGALGKALG YWNRVAGGAV LTSSADLLDS TSVSQAGRDW
PQGLYQSRDN PDTRLFAAGG ICEDNMAGMI AGLAATRRYL GVGSSYGAFM APLGHIAARL
HAISCQARAE RTGEPPLPLV MVCGHAGLKT GEDGPTHADP QALQLLQGNF PAEACVTLTP
WEPAEVFPLL ARSLALRPAV IAPFVTRPKE TVPDREALGL APVSAAVQGL YCLRESGGEP
DIVLVLQGSG VTLTFVNDVL PQLIADGIDP QVFVVSSAEL FDSLEPREQE EVFSVRAAER
AMGITGFTLP TLYRWVTSPL GRQCSLHPFA EGHYPGSGRA EQVLGQAGLD ARGQLAAIYR
YLSLRA
//
