ID C8XCK4_NAKMY Unreviewed; 528 AA.
AC C8XCK4;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Signal transduction histidine kinase regulating citrate/malate metabolism {ECO:0000313|EMBL:ACV77569.1};
DE Flags: Precursor;
GN OrderedLocusNames=Namu_1162 {ECO:0000313|EMBL:ACV77569.1};
OS Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / CIP 104796 / JCM
OS 9543 / NBRC 105858 / Y-104) (Microsphaera multipartita).
OC Bacteria; Actinomycetota; Actinomycetes; Nakamurellales; Nakamurellaceae;
OC Nakamurella.
OX NCBI_TaxID=479431 {ECO:0000313|EMBL:ACV77569.1, ECO:0000313|Proteomes:UP000002218};
RN [1] {ECO:0000313|Proteomes:UP000002218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700099 / DSM 44233 / CIP 104796 / JCM 9543 / NBRC 105858 /
RC Y-104 {ECO:0000313|Proteomes:UP000002218};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Ovchinnikova G., Sims D., Meincke L., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Nakamurella multipartita DSM 44233.";
RL Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACV77569.1, ECO:0000313|Proteomes:UP000002218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700099 / DSM 44233 / CIP 104796 / JCM 9543 / NBRC 105858 /
RC Y-104 {ECO:0000313|Proteomes:UP000002218};
RX PubMed=21304699;
RA Tice H., Mayilraj S., Sims D., Lapidus A., Nolan M., Lucas S.,
RA Glavina Del Rio T., Copeland A., Cheng J.F., Meincke L., Bruce D.,
RA Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G.,
RA Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA Jeffries C.D., Detter J.C., Brettin T., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.,
RA Chen F.;
RT "Complete genome sequence of Nakamurella multipartita type strain (Y-
RT 104).";
RL Stand. Genomic Sci. 2:168-175(2010).
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DR EMBL; CP001737; ACV77569.1; -; Genomic_DNA.
DR RefSeq; WP_015746483.1; NC_013235.1.
DR AlphaFoldDB; C8XCK4; -.
DR STRING; 479431.Namu_1162; -.
DR KEGG; nml:Namu_1162; -.
DR eggNOG; COG3290; Bacteria.
DR HOGENOM; CLU_020211_11_1_11; -.
DR InParanoid; C8XCK4; -.
DR OrthoDB; 9792686at2; -.
DR Proteomes; UP000002218; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR016120; Sig_transdc_His_kin_SpoOB.
DR Pfam; PF17203; sCache_3_2; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR SUPFAM; SSF55890; Sporulation response regulatory protein Spo0B; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ACV77569.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002218};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 178..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 220..285
FT /note="PAS"
FT /evidence="ECO:0000259|SMART:SM00091"
FT REGION 465..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..507
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 528 AA; 55064 MW; 8D4510F847C3DD76 CRC64;
MRSGSSWSLA RRILALQAVV LFVVLAGLLA AVLVDSDAET ERATGERVAS IAAAVASSPD
VVDAVTAPQP AGAEISGPSA VMQPYAESVR TSTATDFIVI MTPEGVRYTH PDPTQIGGTY
LGNRAAALAG GVGIETYTGT LGPSVRAIVP VEQDGTVVAL VSVGVTVDHI NELTNRRLLY
LGLIALGALA VGVAGSLIIA RWVRRQTLGM GPKELARLFT YYDSVLASVH EGMVLLDAKG
TITSINAEGR RLLGLGDAAI GRTPAEAGLP AHLAAMIVDP ESLTDELVLS AERVLVITRR
PVEVRGTVVG AVVTLRDHTE LDALTGELDR VQVFSEALRA QAHESANRMH AVISLIELGE
TDHALSFAVE EMQTAQRLAD RVLEGVGNPA MAALLLAKSA QGAERGIDVT VRAGSYLPPH
AAPDPELVTI VGNLLDNGFD VLTTVAPTDG PRSIKVGLDV LGATIPGAEG VGGGPPRPDP
PGRRRRCRPA RAVRADHRDR HRPRADPRPG PVGVQPGLVD QVGQGAGR
//
