ID C9AA03_ENTCA Unreviewed; 943 AA.
AC C9AA03;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE SubName: Full=Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase {ECO:0000313|EMBL:EEV39314.1};
GN ORFNames=ECBG_01583 {ECO:0000313|EMBL:EEV39314.1};
OS Enterococcus casseliflavus EC20.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=565655 {ECO:0000313|EMBL:EEV39314.1, ECO:0000313|Proteomes:UP000012675};
RN [1] {ECO:0000313|EMBL:EEV39314.1, ECO:0000313|Proteomes:UP000012675}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC20 {ECO:0000313|EMBL:EEV39314.1,
RC ECO:0000313|Proteomes:UP000012675};
RG The Broad Institute Genome Sequencing Platform;
RA Feldgarden M., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Gilmore M., Manson J., Palmer K., Carniol K.,
RA Lander E., Nusbaum C., Galagan J., Birren B.;
RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EEV39314.1, ECO:0000313|Proteomes:UP000012675}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC20 {ECO:0000313|EMBL:EEV39314.1,
RC ECO:0000313|Proteomes:UP000012675};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Russ C., Feldgarden M., Gilmore M., Manson J., Palmer K., Carniol K.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Enterococcus casseliflavus EC20 (899205).";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
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DR EMBL; CP004856; EEV39314.1; -; Genomic_DNA.
DR RefSeq; WP_015508899.1; NZ_AKCC01000001.1.
DR AlphaFoldDB; C9AA03; -.
DR GeneID; 15141027; -.
DR KEGG; ecas:ECBG_01583; -.
DR eggNOG; COG3291; Bacteria.
DR eggNOG; COG4724; Bacteria.
DR HOGENOM; CLU_008357_0_0_9; -.
DR Proteomes; UP000012675; Chromosome.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0033925; F:mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR CDD; cd06547; GH85_ENGase; 1.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR032979; ENGase.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR005201; Glyco_hydro_85.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR13246:SF1; CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE; 1.
DR PANTHER; PTHR13246; ENDO BETA N-ACETYLGLUCOSAMINIDASE; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF03644; Glyco_hydro_85; 1.
DR Pfam; PF00801; PKD; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS50022; FA58C_3; 1.
DR PROSITE; PS50093; PKD; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000012675};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..943
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039710859"
FT DOMAIN 716..786
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 798..941
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
SQ SEQUENCE 943 AA; 103166 MW; EA8B7311BCCCB1FB CRC64;
MTRKISKVGV SLLVLAAATA IGGCTQSEAK TTGKVVYQET AKSTLEKAMD NQPESSYWFP
EDLLAWSFEK DPDAKYNTSV VPLAQRAAKD TLPKMNDTQT AETKVVALSI MNSSTSGNAP
RGINTFDANV FSYWQYIDQL VYWGGSSGEG IIVPPSPDVT DAAHRNGVPV LGTIFFPQTA
HGGKLEWLDT FLAKDEDGNF PIVEKMIEVA NTYGFDGWFI NQETDTAVTS FDDAAEGVEQ
SGADGKGLNE SHAKAMQELI AQFKEQADEH LEIMWYDSMT SDGKMDWQNA LTDKNKAYLV
DAEMNPLADS MFLNFWWTTD KLADKELLKA SNEKAREIGV DPYDLFAGID VQENGYSTPV
RWDLFTDEKG VPYTSLGLYV PSWTYSSAST PDDFQSKENA FWVNNTGDPR ESQLPEATEW
PGISTYALEQ TAITELPFVT NFSLGNGYNY FIEGEKVSSR NWNNRSLQAI LPTYRWVFDH
GKDNDLAVSI NYADAYNGGN ALKLRGQMTK GSTSHMALYQ TAFPVTKKTK LTTTVKATVP
TALDLVVTLA DGSTQTIKGD KEVATDWTTI TYSLKDIKGE VTAIGYDITT KDTSDVYELN
LGQLTIGDKK AEKFAAEALT VEDVLFDEEE GNYAGVRLTW EGAKDKTAAV YEVYQLNDDG
SRSFLAATPA TNHYLNAVER PKGTKTKFAV VAVDRYGNRG KLSDTVEITW PNNQLPKAAF
TASKTLAAPG ETITFTNTSS ANAEAFEWTF EGGDITSSTE ENPQVTYSEP GTYKVTLVAK
NEAGETPLEM AGLITISADA PKELLLLSKD AEATASSFVN DAEAPAFALD GDLSTKWCAT
GNAPHELMID LGRPQTVSEV RLAHAEAGGE GPDMNTRAYT VLVSEDGKDY ELVSRTLKNE
AGNSTNTFAV KKVQYVKISI DKPTQGADSA ARIYEVEVYG MDK
//
