ID C9J847_HUMAN Unreviewed; 114 AA.
AC C9J847;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=ALF transcription elongation factor 3 {ECO:0000313|Ensembl:ENSP00000411383.1};
DE Flags: Fragment;
GN Name=AFF3 {ECO:0000313|Ensembl:ENSP00000411383.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000411383.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000411383.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [2] {ECO:0000313|Ensembl:ENSP00000411383.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC010736; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC018690; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC073118; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC092667; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC093373; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC104782; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC114793; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC133108; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF456685; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; C9J847; -.
DR SMR; C9J847; -.
DR MassIVE; C9J847; -.
DR PeptideAtlas; C9J847; -.
DR ProteomicsDB; 8994; -.
DR Antibodypedia; 32831; 66 antibodies from 17 providers.
DR Ensembl; ENST00000424600.5; ENSP00000411383.1; ENSG00000144218.21.
DR UCSC; uc061mhu.1; human.
DR HGNC; HGNC:6473; AFF3.
DR VEuPathDB; HostDB:ENSG00000144218; -.
DR GeneTree; ENSGT00950000182974; -.
DR ChiTaRS; AFF3; human.
DR Proteomes; UP000005640; Chromosome 2.
DR Bgee; ENSG00000144218; Expressed in cortical plate and 172 other cell types or tissues.
DR ExpressionAtlas; C9J847; baseline and differential.
DR GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR Gene3D; 6.10.250.2670; -; 1.
DR InterPro; IPR007797; AF4/FMR2.
DR PANTHER; PTHR10528; AF4/FMR2 FAMILY MEMBER; 1.
DR PANTHER; PTHR10528:SF16; AF4_FMR2 FAMILY MEMBER 3; 1.
DR Pfam; PF05110; AF-4; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:C9J847,
KW ECO:0007829|PeptideAtlas:C9J847};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT REGION 23..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 89..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 114
FT /evidence="ECO:0000313|Ensembl:ENSP00000411383.1"
SQ SEQUENCE 114 AA; 13270 MW; B096B7E444A0F3A7 CRC64;
MDSFDLALLQ EWDLESLCVY EPDRNALRRK ERERRNQETQ QDDGTFNSSY SLFSEPYKTN
KGDELSNRIQ NTLGNYDEMK DFLTDRSNQS HLVGVPKPGV PQTPVNKIDE HFVA
//
