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Database: UniProt
Entry: C9JAG2_HUMAN
LinkDB: C9JAG2_HUMAN
Original site: C9JAG2_HUMAN 
ID   C9JAG2_HUMAN            Unreviewed;       270 AA.
AC   C9JAG2;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   31-JUL-2019, entry version 62.
DE   SubName: Full=Protein C-ets-2 {ECO:0000313|Ensembl:ENSP00000411086};
DE   Flags: Fragment;
GN   Name=ETS2 {ECO:0000313|Ensembl:ENSP00000411086};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000411086, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000411086, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10830953; DOI=10.1038/35012518;
RG   Chromosome 21 mapping and sequencing consortium;
RA   Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T.,
RA   Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y.,
RA   Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K.,
RA   Polley A., Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D.,
RA   Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W.,
RA   Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S.,
RA   Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E.,
RA   Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P.,
RA   Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H.,
RA   Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E.,
RA   Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F.,
RA   Lehrach H., Reinhardt R., Yaspo M.-L.;
RT   "The DNA sequence of human chromosome 21.";
RL   Nature 405:311-319(2000).
RN   [2] {ECO:0000313|Ensembl:ENSP00000411086}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [3] {ECO:0000213|PubMed:22814378}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA   Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA   Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E.,
RA   Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K.,
RA   Aldabe R.;
RT   "N-terminal acetylome analyses and functional insights of the N-
RT   terminal acetyltransferase NatB.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
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DR   EMBL; AP001040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP001041; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; C9JAG2; -.
DR   MaxQB; C9JAG2; -.
DR   PeptideAtlas; C9JAG2; -.
DR   PRIDE; C9JAG2; -.
DR   ProteomicsDB; 9321; -.
DR   Ensembl; ENST00000456966; ENSP00000411086; ENSG00000157557.
DR   UCSC; uc062acq.1; human.
DR   HGNC; HGNC:3489; ETS2.
DR   OpenTargets; ENSG00000157557; -.
DR   eggNOG; KOG3806; Eukaryota.
DR   eggNOG; ENOG410Z0ZF; LUCA.
DR   GeneTree; ENSGT00940000160202; -.
DR   HOGENOM; HOG000285953; -.
DR   ChiTaRS; ETS2; human.
DR   Proteomes; UP000005640; Chromosome 21.
DR   Bgee; ENSG00000157557; Expressed in 225 organ(s), highest expression level in skin of abdomen.
DR   ExpressionAtlas; C9JAG2; baseline and differential.
DR   GO; GO:0005829; C:cytosol; IDA:HPA.
DR   GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR   GO; GO:0005886; C:plasma membrane; IDA:HPA.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:C9JAG2,
KW   ECO:0000213|PeptideAtlas:C9JAG2, ECO:0000213|ProteomicsDB:C9JAG2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN       85    170       PNT. {ECO:0000259|PROSITE:PS51433}.
FT   NON_TER     270    270       {ECO:0000313|Ensembl:ENSP00000411086}.
SQ   SEQUENCE   270 AA;  30351 MW;  02F9FF74F1BB4643 CRC64;
     MNDFGIKNMD QVAPVANSYR GTLKRQPAFD TFDGSLFAVF PSLNEEQTLQ EVPTGLDSIS
     HDSANCELPL LTPCSKAVMS QALKATFSGF KKEQRRLGIP KNPWLWSEQQ VCQWLLWATN
     EFSLVNVNLQ RFGMNGQMLC NLGKERFLEL APDFVGDILW EHLEQMIKEN QEKTEDQYEE
     NSHLTSVPHW INSNTLGFGT EQAPYGMQTQ NYPKGGLLDS MCPASTPSVL SSEQEFQMFP
     KSRLSSVSVT YCSVSQDFPG SNLNLLTNNS
//
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