ID C9JEK5_HUMAN Unreviewed; 214 AA.
AC C9JEK5;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 29-SEP-2021, sequence version 2.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=STAM binding protein {ECO:0000313|Ensembl:ENSP00000390921.2};
DE Flags: Fragment;
GN Name=STAMBP {ECO:0000313|Ensembl:ENSP00000390921.2};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000390921.2, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000390921.2, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [2] {ECO:0007829|PubMed:21269460}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Burckstummer T.,
RA Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [3] {ECO:0007829|PubMed:23186163}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=23186163;
RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA Mohammed S.;
RT "Toward a comprehensive characterization of a human cancer cell
RT phosphoproteome.";
RL J. Proteome Res. 12:260-271(2013).
RN [4] {ECO:0000313|Ensembl:ENSP00000390921.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC073046; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; C9JEK5; -.
DR SMR; C9JEK5; -.
DR MassIVE; C9JEK5; -.
DR MaxQB; C9JEK5; -.
DR PeptideAtlas; C9JEK5; -.
DR ProteomicsDB; 9867; -.
DR Antibodypedia; 31376; 345 antibodies from 35 providers.
DR Ensembl; ENST00000424659.6; ENSP00000390921.2; ENSG00000124356.17.
DR UCSC; uc061krj.1; human.
DR HGNC; HGNC:16950; STAMBP.
DR VEuPathDB; HostDB:ENSG00000124356; -.
DR GeneTree; ENSGT00940000153710; -.
DR ChiTaRS; STAMBP; human.
DR Proteomes; UP000005640; Chromosome 2.
DR Bgee; ENSG00000124356; Expressed in C1 segment of cervical spinal cord and 216 other cell types or tissues.
DR ExpressionAtlas; C9JEK5; baseline and differential.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR InterPro; IPR015063; USP8_dimer.
DR PANTHER; PTHR12947; AMSH-LIKE PROTEASE; 1.
DR PANTHER; PTHR12947:SF8; STAM-BINDING PROTEIN; 1.
DR Pfam; PF08969; USP8_dimer; 1.
DR SUPFAM; SSF140856; USP8 N-terminal domain-like; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Proteomics identification {ECO:0007829|EPD:C9JEK5,
KW ECO:0007829|MaxQB:C9JEK5};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 13..114
FT /note="USP8 dimerisation"
FT /evidence="ECO:0000259|Pfam:PF08969"
FT REGION 184..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 108..157
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 214
FT /evidence="ECO:0000313|Ensembl:ENSP00000390921.2"
SQ SEQUENCE 214 AA; 24966 MW; 8139B6306AAC7EDE CRC64;
MSDHGDVSLP PEDRVRALSQ LGSAVEVNED IPPRRYFRSG VEIIRMASIY SEEGNIEHAF
ILYNKLFIEK LPKHRDYKSA VIPEKKDTVK KLKEIAFPKA EELKAELLKR YTKEYTEYNE
EKKKEAEELA RNMAIQQELE KEKQRVAQQK QQQLEQEQFH AFEEMIRNQE LEKERLKIVQ
EFGKPSDCHT TVRPAKPPVV DRSLKPGALS NSES
//
