ID C9JLI6_HUMAN Unreviewed; 97 AA.
AC C9JLI6;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=40S ribosomal protein S27 {ECO:0000256|RuleBase:RU000671};
GN Name=RPS27L {ECO:0000313|Ensembl:ENSP00000402423.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000402423.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000402423.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16572171; DOI=10.1038/nature04601;
RA Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M., Stewart S.,
RA Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R.,
RA Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT "Analysis of the DNA sequence and duplication history of human chromosome
RT 15.";
RL Nature 440:671-675(2006).
RN [2] {ECO:0007829|PubMed:21269460}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Burckstummer T.,
RA Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [3] {ECO:0007829|PubMed:24275569}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L.,
RA Ye M., Zou H.;
RT "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver
RT phosphoproteome.";
RL J. Proteomics 96:253-262(2014).
RN [4] {ECO:0000313|Ensembl:ENSP00000402423.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU000671};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|RuleBase:RU000671};
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS27 family.
CC {ECO:0000256|ARBA:ARBA00010919, ECO:0000256|RuleBase:RU000671}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC087612; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; C9JLI6; -.
DR SMR; C9JLI6; -.
DR MassIVE; C9JLI6; -.
DR MaxQB; C9JLI6; -.
DR PeptideAtlas; C9JLI6; -.
DR ProteomicsDB; 10714; -.
DR Antibodypedia; 42798; 109 antibodies from 25 providers.
DR Ensembl; ENST00000439025.1; ENSP00000402423.1; ENSG00000185088.14.
DR UCSC; uc059kbv.1; human.
DR HGNC; HGNC:18476; RPS27L.
DR VEuPathDB; HostDB:ENSG00000185088; -.
DR GeneTree; ENSGT00950000182891; -.
DR PhylomeDB; C9JLI6; -.
DR ChiTaRS; RPS27L; human.
DR Proteomes; UP000005640; Chromosome 15.
DR Bgee; ENSG00000185088; Expressed in seminal vesicle and 202 other cell types or tissues.
DR ExpressionAtlas; C9JLI6; baseline and differential.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 2.20.25.100; Zn-binding ribosomal proteins; 1.
DR HAMAP; MF_00371; Ribosomal_S27e; 1.
DR InterPro; IPR000592; Ribosomal_eS27.
DR InterPro; IPR023407; Ribosomal_eS27_Zn-bd_dom_sf.
DR InterPro; IPR011332; Ribosomal_zn-bd.
DR PANTHER; PTHR11594; 40S RIBOSOMAL PROTEIN S27; 1.
DR PANTHER; PTHR11594:SF2; 40S RIBOSOMAL PROTEIN S27-LIKE; 1.
DR Pfam; PF01667; Ribosomal_S27e; 1.
DR SUPFAM; SSF57829; Zn-binding ribosomal proteins; 1.
DR PROSITE; PS01168; RIBOSOMAL_S27E; 1.
PE 1: Evidence at protein level;
KW Metal-binding {ECO:0000256|RuleBase:RU000671};
KW Proteomics identification {ECO:0007829|EPD:C9JLI6,
KW ECO:0007829|MaxQB:C9JLI6};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Ribonucleoprotein {ECO:0000256|RuleBase:RU000671};
KW Ribosomal protein {ECO:0000256|RuleBase:RU000671};
KW Zinc {ECO:0000256|RuleBase:RU000671};
KW Zinc-finger {ECO:0000256|RuleBase:RU000671}.
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 97 AA; 10886 MW; 4D07EA2761F533A6 CRC64;
MPLARDLLHP SLEEEKKKHK KKRLVQSPNS YFMDVKCPGC YKITTVFSHA QTVVLCVGCS
TVLCQPTGGK ARLTEGISFG ILQPSDEIDD YKCLYLH
//
