ID C9JQS2_HUMAN Unreviewed; 190 AA.
AC C9JQS2;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=SPT20 homolog, SAGA complex component {ECO:0000313|Ensembl:ENSP00000420170.1};
DE Flags: Fragment;
GN Name=SUPT20H {ECO:0000313|Ensembl:ENSP00000420170.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000420170.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000420170.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057823; DOI=10.1038/nature02379;
RA Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L.,
RA Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S.,
RA Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P.,
RA Ambrose K.D., Andrews D.T., Ashwell R.I.S., Babbage A.K., Bagguley C.L.,
RA Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P.,
RA Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P.,
RA Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C.,
RA Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P.,
RA Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L.,
RA Frankish A.G., Frankland J., French L., Garner P., Garnett J.,
RA Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M.,
RA Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D.,
RA Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D.,
RA Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S.,
RA Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J.,
RA Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S.,
RA Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S.,
RA Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R.,
RA Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W.,
RA Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P.,
RA Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L.,
RA Coulson A., Durbin R., Hubbard T., Sulston J.E., Beck S., Bentley D.R.,
RA Rogers J., Ross M.T.;
RT "The DNA sequence and analysis of human chromosome 13.";
RL Nature 428:522-528(2004).
RN [2] {ECO:0007829|PubMed:22814378}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-terminal
RT acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
RN [3] {ECO:0000313|Ensembl:ENSP00000420170.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SPT20 family.
CC {ECO:0000256|ARBA:ARBA00009112}.
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DR EMBL; AL138706; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL391383; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; C9JQS2; -.
DR SMR; C9JQS2; -.
DR MassIVE; C9JQS2; -.
DR MaxQB; C9JQS2; -.
DR PeptideAtlas; C9JQS2; -.
DR ProteomicsDB; 11280; -.
DR Antibodypedia; 49228; 99 antibodies from 20 providers.
DR Ensembl; ENST00000497318.1; ENSP00000420170.1; ENSG00000102710.21.
DR UCSC; uc058wmj.1; human.
DR HGNC; HGNC:20596; SUPT20H.
DR VEuPathDB; HostDB:ENSG00000102710; -.
DR GeneTree; ENSGT00390000013549; -.
DR HOGENOM; CLU_127994_0_0_1; -.
DR ChiTaRS; SUPT20H; human.
DR Proteomes; UP000005640; Chromosome 13.
DR Bgee; ENSG00000102710; Expressed in left testis and 204 other cell types or tissues.
DR ExpressionAtlas; C9JQS2; baseline and differential.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR InterPro; IPR021950; Spt20.
DR InterPro; IPR046468; Spt20-like_SEP.
DR PANTHER; PTHR13526; TRANSCRIPTION FACTOR SPT20 HOMOLOG; 1.
DR PANTHER; PTHR13526:SF8; TRANSCRIPTION FACTOR SPT20 HOMOLOG; 1.
DR Pfam; PF12090; Spt20_SEP; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:C9JQS2,
KW ECO:0007829|MaxQB:C9JQS2};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 76..185
FT /note="Spt20-like SEP"
FT /evidence="ECO:0000259|Pfam:PF12090"
FT NON_TER 190
FT /evidence="ECO:0000313|Ensembl:ENSP00000420170.1"
SQ SEQUENCE 190 AA; 22078 MW; DE4029F8E2F22D78 CRC64;
MQQALELALD RAEYVIESAR QRPPKRKYLS SGRKSVFQKL YDLYIEECEK EPEVKQKLRR
NVNLLEKLVM QETLSCLVVN LYPGNEGYSL MLRGKNGSDS ETIRLPYEEG ELLEYLDAEE
LPPILVDLLE KSQVNIFHCG CVIAEIRDYR QSSNMKSPGY QSRHILLRPT MQTLICDVHS
ITSDNHKWTQ
//
