GenomeNet

Database: UniProt
Entry: C9JRG3_HUMAN
LinkDB: C9JRG3_HUMAN
Original site: C9JRG3_HUMAN 
ID   C9JRG3_HUMAN            Unreviewed;       117 AA.
AC   C9JRG3;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 2.
DT   23-MAY-2018, entry version 59.
DE   SubName: Full=Aspartyl aminopeptidase {ECO:0000313|Ensembl:ENSP00000414739};
DE   Flags: Fragment;
GN   Name=DNPEP {ECO:0000313|Ensembl:ENSP00000414739};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000414739, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000414739, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000414739}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase M18 family.
CC       {ECO:0000256|RuleBase:RU004386}.
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DR   EMBL; AC053503; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF456770; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   MaxQB; C9JRG3; -.
DR   PeptideAtlas; C9JRG3; -.
DR   Ensembl; ENST00000430206; ENSP00000414739; ENSG00000123992.
DR   UCSC; uc061swz.1; human.
DR   EuPathDB; HostDB:ENSG00000123992.18; -.
DR   HGNC; HGNC:2981; DNPEP.
DR   OpenTargets; ENSG00000123992; -.
DR   eggNOG; KOG2596; Eukaryota.
DR   eggNOG; COG1362; LUCA.
DR   GeneTree; ENSGT00390000003164; -.
DR   HOGENOM; HOG000253244; -.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000123992; -.
DR   ExpressionAtlas; C9JRG3; baseline and differential.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 2.30.250.10; -; 1.
DR   InterPro; IPR001948; Peptidase_M18.
DR   InterPro; IPR023358; Peptidase_M18_dom2.
DR   PANTHER; PTHR28570; PTHR28570; 1.
DR   Pfam; PF02127; Peptidase_M18; 1.
DR   PRINTS; PR00932; AMINO1PTASE.
PE   1: Evidence at protein level;
KW   Aminopeptidase {ECO:0000256|RuleBase:RU004386};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Hydrolase {ECO:0000256|RuleBase:RU004386};
KW   Metal-binding {ECO:0000256|RuleBase:RU004386};
KW   Metalloprotease {ECO:0000256|RuleBase:RU004386};
KW   Protease {ECO:0000256|RuleBase:RU004386};
KW   Proteomics identification {ECO:0000213|EPD:C9JRG3,
KW   ECO:0000213|MaxQB:C9JRG3, ECO:0000213|PeptideAtlas:C9JRG3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Zinc {ECO:0000256|RuleBase:RU004386}.
FT   NON_TER     117    117       {ECO:0000313|Ensembl:ENSP00000414739}.
SQ   SEQUENCE   117 AA;  13025 MW;  34F44DF843ED93CC CRC64;
     MTRNSSTIIA FAVGGQYVPG NGFSLIGAHT DSPCLRVKRR SRRSQVGFQQ VGVETYGGGI
     WSTWFDRDLT LAGRVIVKCP TSGRLEQQLV HVERPILRIP HLAIHLQRNI NENFGPN
//
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