ID C9JVH3_HUMAN Unreviewed; 74 AA.
AC C9JVH3;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=ADCYAP receptor type I {ECO:0000313|Ensembl:ENSP00000400893.1};
DE Flags: Fragment;
GN Name=ADCYAP1R1 {ECO:0000313|Ensembl:ENSP00000400893.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000400893.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000400893.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12853948; DOI=10.1038/nature01782;
RA Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA Wilson R.K.;
RT "The DNA sequence of human chromosome 7.";
RL Nature 424:157-164(2003).
RN [2] {ECO:0000313|Ensembl:ENSP00000400893.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC006466; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF510285; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF511015; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF511016; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; C9JVH3; -.
DR SMR; C9JVH3; -.
DR MassIVE; C9JVH3; -.
DR MaxQB; C9JVH3; -.
DR PeptideAtlas; C9JVH3; -.
DR ProteomicsDB; 11867; -.
DR Antibodypedia; 4280; 344 antibodies from 32 providers.
DR Ensembl; ENST00000431811.5; ENSP00000400893.1; ENSG00000078549.16.
DR UCSC; uc064cpe.1; human.
DR HGNC; HGNC:242; ADCYAP1R1.
DR VEuPathDB; HostDB:ENSG00000078549; -.
DR GeneTree; ENSGT00940000157362; -.
DR HOGENOM; CLU_2694198_0_0_1; -.
DR OMA; HLRSCVQ; -.
DR ChiTaRS; ADCYAP1R1; human.
DR Proteomes; UP000005640; Chromosome 7.
DR Bgee; ENSG00000078549; Expressed in cortical plate and 128 other cell types or tissues.
DR ExpressionAtlas; C9JVH3; baseline and differential.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0004999; F:vasoactive intestinal polypeptide receptor activity; IEA:InterPro.
DR Gene3D; 4.10.1240.10; GPCR, family 2, extracellular hormone receptor domain; 1.
DR InterPro; IPR036445; GPCR_2_extracell_dom_sf.
DR InterPro; IPR001879; GPCR_2_extracellular_dom.
DR InterPro; IPR002285; GPCR_2_PACAP_1_rcpt.
DR Pfam; PF02793; HRM; 1.
DR PRINTS; PR01156; PACAPRECEPTR.
DR SUPFAM; SSF111418; Hormone receptor domain; 1.
DR PROSITE; PS50227; G_PROTEIN_RECEP_F2_3; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:C9JVH3,
KW ECO:0007829|ProteomicsDB:C9JVH3};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..74
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002996601"
FT DOMAIN 33..74
FT /note="G-protein coupled receptors family 2 profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50227"
FT NON_TER 74
FT /evidence="ECO:0000313|Ensembl:ENSP00000400893.1"
SQ SEQUENCE 74 AA; 8086 MW; 30399EE431BF952B CRC64;
MAGVVHVSLA ALLLLPMAPA MHSDCIFKKE QAMCLEKIQR ANELMGFNDS SPGCPGMWDN
ITCWKPAHVG EMVL
//
