ID C9JY20_HUMAN Unreviewed; 123 AA.
AC C9JY20;
DT 03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 03-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=FMR1 autosomal homolog 1 {ECO:0000313|Ensembl:ENSP00000419933.1};
DE Flags: Fragment;
GN Name=FXR1 {ECO:0000313|Ensembl:ENSP00000419933.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000419933.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000419933.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16641997; DOI=10.1038/nature04728;
RA Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O.,
RA Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X.,
RA Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT "The DNA sequence, annotation and analysis of human chromosome 3.";
RL Nature 440:1194-1198(2006).
RN [2] {ECO:0007829|PubMed:21269460}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Burckstummer T.,
RA Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [3] {ECO:0000313|Ensembl:ENSP00000419933.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC008009; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC068638; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC108734; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; C9JY20; -.
DR SMR; C9JY20; -.
DR MassIVE; C9JY20; -.
DR MaxQB; C9JY20; -.
DR PeptideAtlas; C9JY20; -.
DR ProteomicsDB; 12197; -.
DR Antibodypedia; 18845; 387 antibodies from 39 providers.
DR Ensembl; ENST00000484958.5; ENSP00000419933.1; ENSG00000114416.19.
DR UCSC; uc062qhv.1; human.
DR HGNC; HGNC:4023; FXR1.
DR VEuPathDB; HostDB:ENSG00000114416; -.
DR GeneTree; ENSGT00950000183189; -.
DR HOGENOM; CLU_167253_0_0_1; -.
DR OMA; WPARITK; -.
DR ChiTaRS; FXR1; human.
DR Proteomes; UP000005640; Chromosome 3.
DR Bgee; ENSG00000114416; Expressed in sperm and 207 other cell types or tissues.
DR ExpressionAtlas; C9JY20; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR GO; GO:0006417; P:regulation of translation; IEA:InterPro.
DR CDD; cd22504; KH_I_FXR1_rpt1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR InterPro; IPR040148; FMR1.
DR InterPro; IPR040472; FMRP_KH0.
DR InterPro; IPR047494; KH_I_FXR1_rpt1.
DR InterPro; IPR041560; Tudor_FRM1.
DR PANTHER; PTHR10603; FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN; 1.
DR PANTHER; PTHR10603:SF6; FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN 1; 1.
DR Pfam; PF17904; KH_9; 1.
DR PROSITE; PS51641; AGENET_LIKE; 1.
PE 1: Evidence at protein level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Proteomics identification {ECO:0007829|EPD:C9JY20,
KW ECO:0007829|MaxQB:C9JY20};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 1..30
FT /note="Agenet-like"
FT /evidence="ECO:0000259|PROSITE:PS51641"
FT NON_TER 123
FT /evidence="ECO:0000313|Ensembl:ENSP00000419933.1"
SQ SEQUENCE 123 AA; 14236 MW; 4118ADE065EEE3A8 CRC64;
MMKGEFYVIE YAACDATYNE IVTFERLRPV NQNKTVKKNT FFKCTVDVPE DLREACANEN
AHKDFKKAVG ACRIFYHPET TQLMILSASE ATVKRVNILS DMHLRSIRTK LMLMSRNEEA
TKH
//
