ID   C9MZ44_9FUSO            Unreviewed;       701 AA.
AC   C9MZ44;
DT   24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   24-NOV-2009, sequence version 1.
DT   24-JAN-2024, entry version 50.
DE   SubName: Full=Glutamate--ammonia ligase, catalytic domain protein {ECO:0000313|EMBL:EEX74032.1};
DE            EC=6.3.1.2 {ECO:0000313|EMBL:EEX74032.1};
GN   Name=glnA {ECO:0000313|EMBL:EEX74032.1};
GN   ORFNames=GCWU000323_01841 {ECO:0000313|EMBL:EEX74032.1};
OS   Leptotrichia hofstadii F0254.
OC   Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Leptotrichiaceae;
OC   Leptotrichia.
OX   NCBI_TaxID=634994 {ECO:0000313|EMBL:EEX74032.1, ECO:0000313|Proteomes:UP000006233};
RN   [1] {ECO:0000313|EMBL:EEX74032.1, ECO:0000313|Proteomes:UP000006233}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0254 {ECO:0000313|EMBL:EEX74032.1,
RC   ECO:0000313|Proteomes:UP000006233};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA   Mardis E.R., Wilson R.K.;
RL   Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC       {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEX74032.1}.
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DR   EMBL; ACVB02000018; EEX74032.1; -; Genomic_DNA.
DR   RefSeq; WP_006805152.1; NZ_GG700633.1.
DR   AlphaFoldDB; C9MZ44; -.
DR   STRING; 634994.GCWU000323_01841; -.
DR   eggNOG; COG3968; Bacteria.
DR   HOGENOM; CLU_024307_0_0_0; -.
DR   Proteomes; UP000006233; Unassembled WGS sequence.
DR   GO; GO:0004356; F:glutamine synthetase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.20.120.1560; -; 1.
DR   Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR   InterPro; IPR040577; Gln-synt_C.
DR   InterPro; IPR008147; Gln_synt_N.
DR   InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR   InterPro; IPR008146; Gln_synth_cat_dom.
DR   InterPro; IPR027303; Gln_synth_gly_rich_site.
DR   InterPro; IPR022147; GSIII_N.
DR   PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR   PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR   Pfam; PF00120; Gln-synt_C; 1.
DR   Pfam; PF18318; Gln-synt_C-ter; 1.
DR   Pfam; PF12437; GSIII_N; 1.
DR   SMART; SM01230; Gln-synt_C; 1.
DR   SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR   PROSITE; PS00181; GLNA_ATP; 1.
DR   PROSITE; PS51986; GS_BETA_GRASP; 1.
DR   PROSITE; PS51987; GS_CATALYTIC; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Ligase {ECO:0000313|EMBL:EEX74032.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006233}.
FT   DOMAIN          62..155
FT                   /note="GS beta-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS51986"
FT   DOMAIN          160..592
FT                   /note="GS catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS51987"
FT   COILED          618..659
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   701 AA;  78697 MW;  CFB3336600AEE9B9 CRC64;
     MENAMKSFGE NVFRDSNLKK RVSKAVFKEF KASQLGETEL SKETAEVIAN AIKDWATKRG
     ATHYCHWFQP LNDLTAEKHD SFLEPTENEE LIYKFSGKNL IKGESDASSF PNGGLRSTFE
     ARGYTIWDTS SYPFIRENKN GVTLYIPTAF ISFTGEALDK KVPLLRSMKY ISGQALRVLR
     AFGNKTSNHV FNTLGVEQEY FLVKKDMFEA RDDLLLTGRT LFGASAPKGQ ELSDHYYGKI
     KEKVINFMSD VDVELWKLGI PSKTRHNEVA PNQFEVAPLF SVANLASDQN QIIMETIEKT
     ALRHDLVALL HEKPFAGVNG SGKHNNWSLG TDDGKNLFSP GKDMKSNTQF LIFVAAVIEA
     VDRYYPMLRY ATATATNDHR LGGHEAPPAI ISVFLGDELT TVLNNIAYKK DAPVSESSKV
     NLSVDVLPAF SMDAGDRNRT SPFAFTGNKF EFRMPGSSST PATSAAVINA MVGKVLSEYA
     DKLEKATEKS LPKVANEIIA NAYKKHHRII FNGNGYSEEW AKEAKKRGLT NEVASNTALR
     KMIDKDVLEL TQEIGMLSEQ ESIARYNAYA ERYITQLSIE SRTLIDIANK NILPSGLKYA
     NLLADHIEKN SKYGKAFIKE QEEILKDVLA NITNLRKEVK SLEKEINRVR NEKDLGKQTD
     LAKEKLVTGL EGLRIPCDNL EKVIDQEYWS FPTYTDLLFK L
//