ID C9P2Q8_VIBME Unreviewed; 785 AA.
AC C9P2Q8;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 24-JAN-2024, entry version 62.
DE RecName: Full=LPS-assembly protein LptD {ECO:0000256|HAMAP-Rule:MF_01411};
DE Flags: Precursor;
GN Name=lptD {ECO:0000256|HAMAP-Rule:MF_01411};
GN ORFNames=VIB_002088 {ECO:0000313|EMBL:EEX37956.1};
OS Vibrio metschnikovii CIP 69.14.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=675813 {ECO:0000313|EMBL:EEX37956.1, ECO:0000313|Proteomes:UP000005604};
RN [1] {ECO:0000313|EMBL:EEX37956.1, ECO:0000313|Proteomes:UP000005604}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIP 69.14 {ECO:0000313|EMBL:EEX37956.1,
RC ECO:0000313|Proteomes:UP000005604};
RG Los Alamos National Laboratory (LANL);
RG National Microbial Pathogen Data Resource (NMPDR);
RA Munk A.C., Tapia R., Green L., Rogers Y., Detter J.C., Bruce D.,
RA Brettin T.S., Colwell R.R., Huq A., Grim C.J., Hasan N.A., Bartels D.,
RA Vonstein V.;
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Together with LptE, is involved in the assembly of
CC lipopolysaccharide (LPS) at the surface of the outer membrane.
CC {ECO:0000256|HAMAP-Rule:MF_01411}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. Interacts with LptE and LptA. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SIMILARITY: Belongs to the LptD family. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_01411}.
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DR EMBL; ACZO01000006; EEX37956.1; -; Genomic_DNA.
DR RefSeq; WP_004396069.1; NZ_ACZO01000006.1.
DR AlphaFoldDB; C9P2Q8; -.
DR STRING; 675813.VIB_002088; -.
DR GeneID; 79886900; -.
DR eggNOG; COG1452; Bacteria.
DR Proteomes; UP000005604; Unassembled WGS sequence.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR Gene3D; 2.60.450.10; Lipopolysaccharide (LPS) transport protein A like domain; 1.
DR HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR InterPro; IPR020889; LipoPS_assembly_LptD.
DR InterPro; IPR007543; LptD_C.
DR InterPro; IPR005653; OstA-like_N.
DR PANTHER; PTHR30189; LPS-ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR30189:SF1; LPS-ASSEMBLY PROTEIN LPTD; 1.
DR Pfam; PF04453; LptD; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237, ECO:0000256|HAMAP-
KW Rule:MF_01411};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01411};
KW Reference proteome {ECO:0000313|Proteomes:UP000005604};
KW Signal {ECO:0000256|HAMAP-Rule:MF_01411}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT CHAIN 25..785
FT /note="LPS-assembly protein LptD"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT /id="PRO_5009008866"
FT DOMAIN 57..189
FT /note="Organic solvent tolerance-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03968"
FT DOMAIN 297..684
FT /note="LptD C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04453"
SQ SEQUENCE 785 AA; 89295 MW; 8BDDE5B400657AB1 CRC64;
MSRFSRTFLA ASISAALFAP QTQAEATVDN SVQELPTLDQ CLVNEPESEN PNPQPIKVKA
DKLEAISGQR ATYSGDVVVL QGQKQIRANN VTLHQQENIV VAEGNVTFSD GQVKATSDRV
TNQLNIDQIT LENTQYQFLC QPGRGHAAYI AKTGKTIYEI EDGSITSCPE GDSAWRLRAS
SIDVDQDAEQ ATFYNPRLEI QNVPVFYLPY LTVPIGDTRK TGFLYPDISY GSRDGFEISV
PFYWNLAPNY DLETTLRYMD NRGTQLNTVF RYLTEFGSGS LKGEFLPDDE LHPEQGKRWG
FQYRHDGIYQ QAWKLDLDYS RVSDVEYFSD LSSGIGNRED GQLMQQARVT YRSSAWDTSL
LARDFQVLTD KDNLPYRLMP QVAFNYYAPE LLRYLDVDIK SHISRFETDA IGKPSATRAH
IEPGISIPLG NTWGTWTTEA RLLATYYQQD LSGVISSDYQ ELEESVSRVI PEFRTHAGIV
LERDTTLFNG YTQTLEPQVQ YLYVPKENQQ NIARYDTTLL QTDYYGLFRS RKYSGVDFIS
AANQVSYGAS TRFFDDQYKE RLNIAFGQIF YIDKGLKSSN TDTSQVEDTQ SNYSAWAVEM
DFNYDDFLFY HGGIQYDIDT SAMQLANSTL EYRFNGGYLQ TNYRYVTKEY IEDTVGDSIP
VSSITRRGIS QAGLLGGYQL SHKWHVTGQY FYDMTTNEAL EWLVGIRYTS DCWYMGFSYS
NQLKDWNRTP NGDYLGFEDP NYENNFSFNI GIIGFGTKVS SSESMAGIKS SDNSLGYGRP
FFLNN
//
