ID C9RBH5_AMMDK Unreviewed; 341 AA.
AC C9RBH5;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 24-JAN-2024, entry version 71.
DE SubName: Full=Galactose-1-phosphate uridylyltransferase {ECO:0000313|EMBL:ACX51602.1};
DE EC=2.7.7.12 {ECO:0000313|EMBL:ACX51602.1};
GN OrderedLocusNames=Adeg_0450 {ECO:0000313|EMBL:ACX51602.1};
OS Ammonifex degensii (strain DSM 10501 / KC4).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Ammonifex.
OX NCBI_TaxID=429009 {ECO:0000313|EMBL:ACX51602.1, ECO:0000313|Proteomes:UP000002620};
RN [1] {ECO:0000313|EMBL:ACX51602.1, ECO:0000313|Proteomes:UP000002620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10501 / KC4 {ECO:0000313|Proteomes:UP000002620};
RG US DOE Joint Genome Institute;
RA Kerfeld C., Goodner B., Huber H., Stetter K., Lucas S., Copeland A.,
RA Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L.,
RA Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Ovchinnikova G., Richardson P.;
RT "Complete sequence of chromosome of Ammonifex degensii KC4.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|PIRSR:PIRSR000808-3};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|PIRSR:PIRSR000808-3};
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DR EMBL; CP001785; ACX51602.1; -; Genomic_DNA.
DR RefSeq; WP_015738480.1; NC_013385.1.
DR AlphaFoldDB; C9RBH5; -.
DR STRING; 429009.Adeg_0450; -.
DR KEGG; adg:Adeg_0450; -.
DR eggNOG; COG1085; Bacteria.
DR HOGENOM; CLU_029960_1_0_9; -.
DR OrthoDB; 9769064at2; -.
DR UniPathway; UPA00214; -.
DR Proteomes; UP000002620; Chromosome.
DR GO; GO:0008108; F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0033499; P:galactose catabolic process via UDP-galactose; IEA:InterPro.
DR Gene3D; 3.30.428.10; HIT-like; 2.
DR InterPro; IPR032576; DUF4921.
DR InterPro; IPR001937; GalP_UDPtransf1.
DR InterPro; IPR036265; HIT-like_sf.
DR NCBIfam; TIGR00209; galT_1; 1.
DR PANTHER; PTHR42763; ADP-GLUCOSE PHOSPHORYLASE; 1.
DR PANTHER; PTHR42763:SF1; UDP-GLUCOSE--HEXOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF16268; DUF4921; 1.
DR PIRSF; PIRSF000808; GalT; 1.
DR SUPFAM; SSF54197; HIT-like; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PIRSR:PIRSR000808-3};
KW Nucleotidyltransferase {ECO:0000313|EMBL:ACX51602.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002620};
KW Transferase {ECO:0000313|EMBL:ACX51602.1};
KW Zinc {ECO:0000256|PIRSR:PIRSR000808-3}.
FT DOMAIN 140..325
FT /note="DUF4921"
FT /evidence="ECO:0000259|Pfam:PF16268"
FT ACT_SITE 165
FT /note="Tele-UMP-histidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000808-1"
FT BINDING 39
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR000808-3"
FT BINDING 42
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR000808-3"
FT BINDING 112
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR000808-3"
FT BINDING 163
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR000808-3"
SQ SEQUENCE 341 AA; 39381 MW; 26D5261341A5763B CRC64;
MPEWRKDPVV DRWVAVSTER AKRPTDYRPP LERKKQERCP LCVGHEGDTP PEVMAFRHPG
SLPDHPGWWV RVVPNKFPAC RVEEEDIVRP HGPYQWRCGV GAHEVIVETP EHVPNLVNQS
EGQIAEVIWA WRARLLDLRR DTRFKYIQIF KNKGSVAGAS LEHTHSQLIA LPMVPAEIQA
ELTGVKVYRE EKGSCVFCDL WRYELEAGER VVEESSHFLC FVPYAARFPF EMWLVPKRHK
PDFGAIEEGE VCDLAWLLKR TLYRLAQTVF DPPFNLVLHT APVNVPEPVD YHWHIEILPR
LTIMAGFELG TGYYINPTPP EMAAAALREQ EVEERMVSHF V
//
