ID C9RJN8_FIBSS Unreviewed; 481 AA.
AC C9RJN8;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=Anthranilate synthase component 1 {ECO:0000256|ARBA:ARBA00020653};
GN Name=trpE {ECO:0000313|EMBL:ADL24893.1};
GN OrderedLocusNames=FSU_0540 {ECO:0000313|EMBL:ADL24893.1};
OS Fibrobacter succinogenes (strain ATCC 19169 / S85).
OC Bacteria; Fibrobacterota; Fibrobacteria; Fibrobacterales; Fibrobacteraceae;
OC Fibrobacter.
OX NCBI_TaxID=59374 {ECO:0000313|EMBL:ADL24893.1, ECO:0000313|Proteomes:UP000000517};
RN [1] {ECO:0000313|Proteomes:UP000000517}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19169 / S85 {ECO:0000313|Proteomes:UP000000517};
RA Durkin A.S., Nelson K.E., Morrison M., Forsberg C.W., Wilson D.B.,
RA Russell J.B., Cann I.K.O., Mackie R.I., White B.A.;
RT "Complete sequence of Fibrobacter succinogenes subsp. succinogenes S85.";
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SUBUNIT: Heterotetramer consisting of two non-identical subunits: a
CC beta subunit (TrpG) and a large alpha subunit (TrpE).
CC {ECO:0000256|ARBA:ARBA00011575}.
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DR EMBL; CP002158; ADL24893.1; -; Genomic_DNA.
DR RefSeq; WP_012819981.1; NC_017448.1.
DR AlphaFoldDB; C9RJN8; -.
DR STRING; 59374.FSU_0540; -.
DR GeneID; 34754499; -.
DR KEGG; fsc:FSU_0540; -.
DR PATRIC; fig|59374.8.peg.522; -.
DR eggNOG; COG0147; Bacteria.
DR HOGENOM; CLU_006493_9_3_0; -.
DR OrthoDB; 9803598at2; -.
DR Proteomes; UP000000517; Chromosome.
DR GO; GO:0004049; F:anthranilate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR019999; Anth_synth_I-like.
DR InterPro; IPR006805; Anth_synth_I_N.
DR InterPro; IPR015890; Chorismate_C.
DR PANTHER; PTHR11236; AMINOBENZOATE/ANTHRANILATE SYNTHASE; 1.
DR PANTHER; PTHR11236:SF48; ISOCHORISMATE SYNTHASE MENF; 1.
DR Pfam; PF04715; Anth_synt_I_N; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR PRINTS; PR00095; ANTSNTHASEI.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:ADL24893.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 30..166
FT /note="Anthranilate synthase component I N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04715"
FT DOMAIN 216..469
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 481 AA; 53407 MW; 8B4D00CD5D29B826 CRC64;
MTKITHITER PGYAPRTDSI YVALPGERYT PFSLAKKLGA KAIFESASFD HGRSRYSTLM
VDEGFRLRQN DKNVSIVVDG KESEFLAEGD GDILDALLKI SAENTVPPNQ IPIPSSGVGY
LGYEFCARCD TIRLAPQVDE LNIPEAEFLV GHIYIVFDHF TEKLHLFALN YEEHQIDLKA
AIEKVKARLA DLDFSYLAPE KQYSKGITMT DLEQSRKEYV EKVAALQKHI VAGNIVQAVP
SRRIQFASDI EALDIYRRLR TVNPSPYMFF LDYGTHQFIG ASPESLIRVR EGIATIHPIA
GTRRRGKDDA EDEALMKNLK GDPKERAEHL MLVDLARNDL GRVCDAGTVE TTKYMECEKF
SHVIHLVSDV QGRVSKNKKA IEVLRSSFPA GTVSGAPKIS AIEILSGLEK IKRRFYAGAV
GYIESDGDLD FCIAIRCCLK QGKTISLQAG GGIVAASNAD REFEETNEKL GAIRAVLEGE
N
//
