ID C9RNN7_FIBSS Unreviewed; 1655 AA.
AC C9RNN7;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=ATP-dependent DNA helicase, RecQ family/UvrD/REP helicase domain protein {ECO:0000313|EMBL:ADL27140.1};
GN OrderedLocusNames=FSU_1321 {ECO:0000313|EMBL:ADL27140.1};
OS Fibrobacter succinogenes (strain ATCC 19169 / S85).
OC Bacteria; Fibrobacterota; Fibrobacteria; Fibrobacterales; Fibrobacteraceae;
OC Fibrobacter.
OX NCBI_TaxID=59374 {ECO:0000313|EMBL:ADL27140.1, ECO:0000313|Proteomes:UP000000517};
RN [1] {ECO:0000313|Proteomes:UP000000517}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19169 / S85 {ECO:0000313|Proteomes:UP000000517};
RA Durkin A.S., Nelson K.E., Morrison M., Forsberg C.W., Wilson D.B.,
RA Russell J.B., Cann I.K.O., Mackie R.I., White B.A.;
RT "Complete sequence of Fibrobacter succinogenes subsp. succinogenes S85.";
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR EMBL; CP002158; ADL27140.1; -; Genomic_DNA.
DR RefSeq; WP_014545625.1; NC_017448.1.
DR STRING; 59374.FSU_1321; -.
DR GeneID; 34755227; -.
DR KEGG; fsc:FSU_1321; -.
DR PATRIC; fig|59374.8.peg.1273; -.
DR eggNOG; COG0210; Bacteria.
DR eggNOG; COG0514; Bacteria.
DR eggNOG; COG0847; Bacteria.
DR HOGENOM; CLU_002862_0_0_0; -.
DR OrthoDB; 9760034at2; -.
DR Proteomes; UP000000517; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF13245; AAA_19; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13361; UvrD_C; 2.
DR SMART; SM00487; DEXDc; 2.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}.
FT DOMAIN 281..462
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 490..637
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 1060..1259
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 1081..1088
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1655 AA; 189129 MW; 43BC1EF6990636D3 CRC64;
MADFSKFLFF DLEYNPETQK VREYGYILGE EEVRERNTAK LEQAASKAKY IVGHNVLRHD
APILRQYFSI DFPNIHALDT LMLSSLLFPR KPYHKLRKEY LHNEDEPSNP LEDTKLCKKL
LEDCIKKWDN YPWQLQYLLF QFLKNEPGFA PFFELVDTPN PIKLRLKLSE IQHWFTENYE
KTICLRQNFQ NEWAAYRAEW CFLLTLFHEE GPSDYVPHWV RYQYPHLENI LHRRRLVPCG
NPQCPYCSEQ LNSTKQLKKW FGFDNFRSFN GEQVPLQQQV VESAMRGESL LAVFPTGGGK
SMTFQLPALI AGTQIGALTV VISPIVALMK DQVDVLEKRR QIGDAAYINS MLSPAERKDV
IEKVNNGEKN ILYISPESLR SNTTFNLLKH RRVERIVVDE AHCFSGWGHD FRVDYLYLAD
FLKDLQKEKN LETPIPVSCF TATAKQSVVD DICNYFKERL NLDLIKFISP AKRTNLTYKV
LESSESPNER RKQLVNVLRD YNGPKIIYAS KVKTTESLAE ELHNRGFASA CYNGKMESEK
KMTIQDQFQN GEVDTMVATT AFGMGVDKDN VELVAHYEIS STLENYVQEA GRAGRDPKLQ
ASCIALFNPK DLDTNFQILQ QSKLSAQEIS AVWRVLKKAA GNQNRLIMSA LEIADQCGWT
EKETDASVNT TKVKLAILVL EEQGFLKRKR NRTQMYGSSI TVESAEQARE AIGSDKIEIL
NSVESIAYRI IHHIISKRWT RSPECALDEL TVNLGLTREQ ANDGLRLLRS LHLLNEDDDW
SARLQRKGND TPRSLLKAAY ELQEELLKAC EGKGINDRFV LDMTKLNSLL NQRGDAVGAS
TSRRNLFIFR GILRYWAHES VAEIHLVEAG HQVYQIEFLV PPESVKENLR KQWKLFDKVI
DTLIEMQKEQ TRQNGNIVWF SLNGLMKRMY KEKGEIAVAR IEKQKQLEYA LLFLHLVGSI
TLDHGLVVFY TGLVMELNPE AKQRNFTAKD FEMLNTHYKH KAEAIHIVGE YAKMMLIDEK
AAQQLLDDYF VMDIADFRLK YMQGIEQMES VSDELKRKIE SVNDEQRKII KSRKKHILVG
AGPGSGKTHL LVHKVASLLW IEEAKPDSIL CLTYTRAACR ELKKRLFDLA GPLAAKVNIT
TFHSLAFSIL GVQGNKKALE NADDVVSKAA ELLESGEEAG VGAPTVILVD EFQDLSAGEY
RLLRALYDLG EKDPRVIVVG DDDQSIFAFR GSSSEYFQKF ADEFPNTEKF YLTTNYRSVA
GLVRANAKLL ELMTERVKEG SQQLALKHSQ AELAFYEEGD KATAAFGAAE ILAQKFKSNP
TESYCILTRE NAEAFLAAAK LEEKQVPYRM LKGRDKDKCP IEKTREILGF YAILQEDPRV
GKFPWSAKEF KRIAEDYKTS HPTESSFELL DALIDDFIET ETACGEDSIT LGDFNQYLSE
VSYSDFSSKN MGAVSIGTMH SAKGLEWDNV ILALGSWVLK DADEKKAQEN YRLLYVAATR
AKKSLTIIGD EKMLPHEWIS HFAKQGKVNS VKIPNVLHIE TGLSDVNLGH LLENEKNRNR
VRYIQSKLET SSLQSDVSVN FSQEFHNYNT NINGRLIAAF SNDFSKKCIA YLQRYGYKPT
TTATLSQVVR WTSDDGQETW VPLFRVEFAK DSINK
//
