ID C9S7C2_VERA1 Unreviewed; 729 AA.
AC C9S7C2;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000313|EMBL:EEY14707.1};
GN ORFNames=VDBG_00816 {ECO:0000313|EMBL:EEY14707.1};
OS Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136)
OS (Verticillium wilt of alfalfa) (Verticillium albo-atrum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=526221 {ECO:0000313|Proteomes:UP000008698};
RN [1] {ECO:0000313|Proteomes:UP000008698}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VaMs.102 / ATCC MYA-4576 / FGSC 10136
RC {ECO:0000313|Proteomes:UP000008698};
RX PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT "Comparative genomics yields insights into niche adaptation of plant
RT vascular wilt pathogens.";
RL PLoS Pathog. 7:E1002137-E1002137(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS985214; EEY14707.1; -; Genomic_DNA.
DR RefSeq; XP_003009133.1; XM_003009087.1.
DR AlphaFoldDB; C9S7C2; -.
DR SMR; C9S7C2; -.
DR STRING; 526221.C9S7C2; -.
DR GeneID; 9530708; -.
DR KEGG; val:VDBG_00816; -.
DR eggNOG; ENOG502QRGH; Eukaryota.
DR HOGENOM; CLU_005987_0_0_1; -.
DR OMA; PPVTHDM; -.
DR OrthoDB; 1561at2759; -.
DR UniPathway; UPA00753; -.
DR Proteomes; UP000008698; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006656; P:phosphatidylcholine biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 2.60.40.2840; -; 1.
DR InterPro; IPR007318; Phopholipid_MeTrfase.
DR PANTHER; PTHR32138; PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR32138:SF0; PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE; 1.
DR Pfam; PF04191; PEMT; 2.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Methyltransferase {ECO:0000313|EMBL:EEY14707.1};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000008698};
KW Transferase {ECO:0000313|EMBL:EEY14707.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 79..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 729 AA; 81952 MW; 0721559D63FC5608 CRC64;
MSSATDVSAG AASVRLRQKP ALSPSSNQQS EPAAQQDSDQ KPKKTFGRTP DGTVFTVPTT
HDMVSQLLDP RQPKNLSDVL VLAFLGGMIA IAYLLPWGLK RPVFALIFLF WRASYNIGIG
YLLTIQSQHR RLETWATRWK LFEHPSTGKQ PRPWLYNTLK RELEAKIPED YEFEKAPMEY
NTWLTFRRVV DLILMCDFVS YCLFAIICGH KPEARASSLA PCELTFDGVF EMAPHPMYSI
GYAGYYGISM MAASYEVLFI SIVAHLAQFA FLVIVENPLI EKGVQHAPTS VYDSLGEFGW
FFGDFFYDHQ AKLTYTSIYR FLNNPERVFG TAGLWGAALI TWSRAIFVMA LFSQILTLGF
IAYVEKPHMQ KIYGRSLREE AGLTKFIKRS LPPPVQGWQR GVDKVLDDTS HFVEDFLEAA
RPKFTSGVKT IVRDTTALFN TYPARFTITR LSLDLAGFNP KHYSLVVEGT PSSLSAANER
ATGKESVTAR FPHRVETLMF EYGAPLKVKW RAPANHGSKD WIGLYMVTDN HSREATEVPS
LGRWVPTTPG QYDATADKAI LVPDHPVSSD GSTTLVEGEV VFEGDRLWWT SGVFEFRYHH
NGKHNVMTIS QPFEVRIGRF DEEDVEVDSL GVYEKAVEQA LLPLVRNCLD RDPDIAPTTV
DEPFGGHVER DSKYAKRVVY AIHQAFGVEF APAVVPADGN VKKLAWRICN AKQVLHVSIQ
GNDNAIREG
//
