ID C9SB65_VERA1 Unreviewed; 1713 AA.
AC C9SB65;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=phospholipase D {ECO:0000256|ARBA:ARBA00012027};
DE EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
GN ORFNames=VDBG_01724 {ECO:0000313|EMBL:EEY15615.1};
OS Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136)
OS (Verticillium wilt of alfalfa) (Verticillium albo-atrum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=526221 {ECO:0000313|Proteomes:UP000008698};
RN [1] {ECO:0000313|Proteomes:UP000008698}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VaMs.102 / ATCC MYA-4576 / FGSC 10136
RC {ECO:0000313|Proteomes:UP000008698};
RX PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT "Comparative genomics yields insights into niche adaptation of plant
RT vascular wilt pathogens.";
RL PLoS Pathog. 7:E1002137-E1002137(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798};
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DR EMBL; DS985215; EEY15615.1; -; Genomic_DNA.
DR RefSeq; XP_003007536.1; XM_003007490.1.
DR STRING; 526221.C9SB65; -.
DR GeneID; 9534999; -.
DR KEGG; val:VDBG_01724; -.
DR eggNOG; KOG1329; Eukaryota.
DR HOGENOM; CLU_000690_0_1_1; -.
DR OMA; DSLWTKH; -.
DR OrthoDB; 335467at2759; -.
DR Proteomes; UP000008698; Unassembled WGS sequence.
DR GO; GO:0070290; F:N-acylphosphatidylethanolamine-specific phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0004630; F:phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01254; PH_PLD; 1.
DR CDD; cd09138; PLDc_vPLD1_2_yPLD_like_1; 1.
DR CDD; cd09141; PLDc_vPLD1_2_yPLD_like_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR InterPro; IPR015679; PLipase_D_fam.
DR PANTHER; PTHR18896:SF76; PHOSPHOLIPASE; 1.
DR PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR Pfam; PF00614; PLDc; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022963};
KW Reference proteome {ECO:0000313|Proteomes:UP000008698}.
FT DOMAIN 837..864
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 1141..1168
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT REGION 1..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1245..1271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1478..1667
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..200
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..256
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1518..1537
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1551..1570
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1608..1636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1713 AA; 192398 MW; 13744149DBA4BC82 CRC64;
MGDNRRDDSV SPMTRSPKPT RVAIAGSPDR PASPLPSILK SSPLAGSPNN VESTTEARDY
MNGGLPHRHQ SPVDPLGRPI PPALYVPSTL NNSSDMNDRT PDPPFLQENG GNSEPTSPGG
GRRSVQFARA DVVLDAPPAH THSRNTSWDD PAKSLSSSLM NKLKQFAGSS TQIPRSPSSG
ALGEAGSQAL NASPTVTRGG SRIPGTLAEE GSDIDADAEE TADEGAVSDT IQSRLGLRRR
LSMPDPPDHQ HGLSEGEGRD QLTTPSWMRG NSWIVGSTRS LRNESRDTGG PSTRGPGHVR
RITVLGGGGA SDGDAMTPRR PFFSGERAST FGVQKWKQVK NTLKLLRQKK EDRFDFAKSA
ELMAELRAGA PAALMLASMI QRDEHGNKRI PVLLEQWTII RTIKDVYNLH VRYKFAMSND
KFIHGRADIG SRPKQPKFPW AAFPYLRGAR TKDESEEDDM ASVRGDDPAE QTPGERTVDE
TADETDGRPQ GGRRKKSRLG MLGMRRRSTG LTDPGETSAL EGHAEMMQSR RRYVERQRRV
LEKYMQDMVR WLMFRADSNR LCKFLELSAL GVRLAAEGSY HGKECYLHIQ SSKGLDFRRV
LTPEKVIARH SRKWFLVRSS YIVCVESPEN MLVYDVYLVD AKFRIASKKS SLKHIGSSGT
REIDLTKEPP PDKHHTLTLH TSERKVKLFS RNQAVLKQFE DSIAEMLKQT KWHSVNRFDS
FAPVRQGVFA QWLVDGRDYM WNVSRAISMA RDVIYIHDWW LSPELYMRRP PAISQKWRLD
RLLQRKAREG VKVFVIVYRN VEAAIPIDSE YTKHSLLNLH PNIFVQRSPN QFKKNQFFFA
HHEKLCVIDH DIAFVGGIDL CFGRWDCPQH PCVDDKPTGF EQSEQPKDAL HCQLFPGKDY
SNARVQDFYK LNEPYEEMYD RGKIPRMPWH DIGMQVVGQP ARDLTRHFVQ RWNYIRRGRT
TTRPLPFLLP PPDVKPGEME GLGLTGTCEV QILRSACNWS LGIDDPEHSI QNAYIKMIED
SDHFVYMENQ FFITSTEVMN TKIVNRIGDA LVERIIRAYN NEEDWKACIV IPLLPGFQSR
VDEQEGTSVR LILQCQFYSI CRGENSIFGR LRAAGIEPED YIQFYSLRQW GKMGSGELVT
EQLYIHAKCI IVDDRVALIG SANINERSLR GDRDSELAAI VRDTDMIWST MGGKPYRVGR
FAHTLRLRLM REHLGLDVDE ILEEERQAEL DKEEEMAAQM DEIYNDEPTT PGFDADEAGP
SNSAPSASNE DHLWLSDARR FNRDADATPL SRSEAASMVE EKDLRVFNTE HALEVEGYGP
DHWKAAEKRG LDTGRDSVII NGREVLVHNN DKLPPMPALN RRTTDQLGLL RANQLPTLPA
VDDTDIGGPP VYLDVNGQPS MGPAHPLAAD IKQARLDKDC MRDPVNFSFM DEIWNRVAEN
NTKLFRRVFR CMPDSEVLTW NDYRDFTSYN ERFVNSMQGK KAGEEPEVAP EAAEQSNAAG
SGGAGIGIPG PAAIAKAATD KMEEKTGLDK VKEHVHPPKI MVPSNTTGNE EFNEKADRAA
RRDKVDHQGV APRNGADPEK SIPFDAPSPI LPAGDTPFPA FDGAEEPSTL PTREKSRDRR
ATFQPTEKEP ARDRDRSASG QQNQGSVRRR RRATTKGSRR GGTPEDVLPA AEAEELLNLI
QGHLVQFPYD WLATEEQNGN WGFQVDGVAP LQI
//
