ID   C9SJT1_VERA1            Unreviewed;       496 AA.
AC   C9SJT1;
DT   24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   24-NOV-2009, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE            EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
GN   ORFNames=VDBG_05804 {ECO:0000313|EMBL:EEY19695.1};
OS   Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136)
OS   (Verticillium wilt of alfalfa) (Verticillium albo-atrum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX   NCBI_TaxID=526221 {ECO:0000313|Proteomes:UP000008698};
RN   [1] {ECO:0000313|Proteomes:UP000008698}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VaMs.102 / ATCC MYA-4576 / FGSC 10136
RC   {ECO:0000313|Proteomes:UP000008698};
RX   PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA   Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA   Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA   Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA   Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA   Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA   Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT   "Comparative genomics yields insights into niche adaptation of plant
RT   vascular wilt pathogens.";
RL   PLoS Pathog. 7:E1002137-E1002137(2011).
CC   -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC       pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC       {ECO:0000256|ARBA:ARBA00005190}.
CC   -!- SIMILARITY: Belongs to the FGGY kinase family.
CC       {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
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DR   EMBL; DS985219; EEY19695.1; -; Genomic_DNA.
DR   RefSeq; XP_003004691.1; XM_003004645.1.
DR   AlphaFoldDB; C9SJT1; -.
DR   STRING; 526221.C9SJT1; -.
DR   GeneID; 9536664; -.
DR   KEGG; val:VDBG_05804; -.
DR   eggNOG; KOG2517; Eukaryota.
DR   HOGENOM; CLU_009281_2_3_1; -.
DR   OMA; HKTDATN; -.
DR   OrthoDB; 2734344at2759; -.
DR   UniPathway; UPA00618; UER00672.
DR   Proteomes; UP000008698; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR   InterPro; IPR018485; FGGY_C.
DR   InterPro; IPR018484; FGGY_N.
DR   InterPro; IPR005999; Glycerol_kin.
DR   NCBIfam; TIGR01311; glycerol_kin; 1.
DR   PANTHER; PTHR10196:SF75; GLYCEROL KINASE; 1.
DR   PANTHER; PTHR10196; SUGAR KINASE; 1.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   PIRSF; PIRSF000538; GlpK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   PROSITE; PS00933; FGGY_KINASES_1; 1.
DR   PROSITE; PS00445; FGGY_KINASES_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW   Kinase {ECO:0000256|RuleBase:RU003733, ECO:0000313|EMBL:EEY19695.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008698};
KW   Transferase {ECO:0000256|RuleBase:RU003733}.
FT   DOMAIN          9..180
FT                   /note="Carbohydrate kinase FGGY N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00370"
FT   DOMAIN          256..446
FT                   /note="Carbohydrate kinase FGGY C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02782"
SQ   SEQUENCE   496 AA;  53787 MW;  E7095D68375F71A9 CRC64;
     MSKNIEFVGA IDQGTTSSRF LIFNPKGEVV ATHQLEFKQL YPQPGWHEHD PEELISSVET
     CIDGAVKAFE TQGHSKSQIK AVGITNQRET TVVWDKNTGK ALYNAIVWTD TRAQELVRRL
     KHRLGAGELT KRCGLPLSTY PSVSKLLWLI ENVKEVKAAY DAGNLAFGTV DAWLVYKLNG
     GPPPNIHTRA YDDELIDWFR VDRNKVQLPT IVRSADSDVY GSLASTSLKG IKIAGVLGDQ
     SAALVGQKGF FPGLAKNTYG TGCFLLYNVG DKPVISSHGL MTTIAFDFGD KGGCAYALEG
     SIAVAGSSVK FLVDNLGFIE ESSKLSALAE TVEDNGGCTF VTAFSGLFAP YWIDDARGTI
     FGITAYTKRG HIARATLEAT CFQTKAILDS MEKDSGAALT ELAVDGGMCN SDLIMQTQSD
     LIGMPVNRPA MRETTAFGAA IAAGLAVGVW DSFDDLKNTN TEGRTIFKPQ INDDESAKRF
     KKWEKAVQMS AGWANE
//