ID C9SQ17_VERA1 Unreviewed; 1436 AA.
AC C9SQ17;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22 {ECO:0000313|EMBL:EEY20942.1};
GN ORFNames=VDBG_07052 {ECO:0000313|EMBL:EEY20942.1};
OS Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136)
OS (Verticillium wilt of alfalfa) (Verticillium albo-atrum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=526221 {ECO:0000313|Proteomes:UP000008698};
RN [1] {ECO:0000313|Proteomes:UP000008698}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VaMs.102 / ATCC MYA-4576 / FGSC 10136
RC {ECO:0000313|Proteomes:UP000008698};
RX PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT "Comparative genomics yields insights into niche adaptation of plant
RT vascular wilt pathogens.";
RL PLoS Pathog. 7:E1002137-E1002137(2011).
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DR EMBL; DS985222; EEY20942.1; -; Genomic_DNA.
DR RefSeq; XP_003002481.1; XM_003002435.1.
DR STRING; 526221.C9SQ17; -.
DR GeneID; 9527476; -.
DR KEGG; val:VDBG_07052; -.
DR eggNOG; KOG0920; Eukaryota.
DR HOGENOM; CLU_001832_1_3_1; -.
DR OMA; TFPVEMK; -.
DR OrthoDB; 1095660at2759; -.
DR Proteomes; UP000008698; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF197; DEPENDENT RNA HELICASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G07950)-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:EEY20942.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008698}.
FT DOMAIN 641..812
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 887..1064
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 328..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..93
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1436 AA; 159289 MW; 62D42F6410F5050F CRC64;
MAKKKKPANN PARGFATTSV ASKPRPEVLE GAEIAPDVAS QPKHNAKGGA ATASGAQTPA
TNAAGACGHQ RLCCRKQGPE PRKSLRGDFE GVRVAVDGRG PVSPPRTSRQ NTAPAQDAPR
EDMVIRLWAL QQTLSSVGFP QERVQAVTQH ILDISPNIPA TAKDSIWGLE EAMEWLAREL
TADELPDYEG RGKPSLKPTE TPADSPLTSG TTTPGYSEAP FRQTKGKHGA QAQAQIPSKK
AAITCDSDIE PDDLIPVYIE TKSKLFSAER AHQESKRQKP FVPTDEGVIP RLQAKLERIE
KDVLFDKYPA EQQWKARKMA LEKELAAMRR QKAQDATSEA TETSPEPTEE PLTGDVNDEA
ERMAAEILAE GAGDDDDDAL AGLFDSLPTN EVDADTGKTN TVVNGPDGVK VTIRSFGTWT
GVSPMRALEE ACRARDSSVK LHYGLISEVP FANRHMLNIS WSKTQAIPPA SSDDTVHVSA
YAKAFTYSMR SVAAPDKKQS EAFIATWALY HIFGPSQKEE KVGLRLPPVW KELWAELAEA
RKSSLDAKDR EEIRMLRAMV RQRQDQELED GVILPSAFRG RGAARNAGEL TEGASDPAKR
NFGGPEYFQQ IWAKKSSTPR YQTMLQSRMQ LPMWQFRQQV VDTVDREQVV IICGETGCGK
STQVPSFLLE HQLAQGKPCK IYCTEPRRIS AISLARRVSE ELGEGRGDIG TPRSLVGYSI
RLEANTSKET RLVFATTGIV MRMLEGSNDL REVTHLVLDE VHERSIDSDF LLIVLKKLML
RRKDLKVVLM SATVDAERFS NYLGNAPVLT VPGRTFPVQV RYLEDAIELT GFSTGQASQE
KMVDLDDDVE TETEGPKTTV GSELAKYSAK TRNTLAQMDE YRIDFDLIVQ LIAKIAADPS
YSQFSKAILV FLPGIAEIRT INDMLLGDPS FAKDWLIYPL HSSIATEDQE AAFLVPPPGI
RKVVLATNIA ETGITIPDVT CVIDTGKHRE MRFDERRQLS RLIDTFISRA NAKQRRGRAG
RVQEGLCFHM FTKHRHDALI SDQQTPEMLR LSLQDLAIRV KICKIGGIEE TLSEALDAPS
AKNIRRAVDA LIDVRALTNA EELTPLGHQL ARLPLDVFLG KLILLGTVFK CLDMAITVAA
ILSSKSPFSA PFGQRAQADM VRMGFRRGDS DLLTIYNAYL AWRRVCQTTS ASGGKEFQFC
RKNFLSQQTL ANIEDLKGQL MVSLVDSGFL SLTDDERRAL NRLRYSNNSR RRHQQFFEIP
QRVNLNSEND AITTAVIAWS FYPKLLVRDT PGSRGLRNVG NNQSISLHPS SVNKGHNEIR
WLSYYHIMQS KAVYHAHETS AADAFAIALL CGDVKADMFA GVLVLDGNRA RFALPDWKTM
LVLKVLRTRL REVLTRAFKQ PGKLPTAQQE RWLEVWQKIF SQDAHKENGS TAVTKA
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