ID C9Z050_STRSW Unreviewed; 553 AA.
AC C9Z050;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=PROBABLE FATTY-ACID-CoA LIGASE FADD19 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) {ECO:0000313|EMBL:CBG75436.1};
GN Name=fadD19 {ECO:0000313|EMBL:CBG75436.1};
GN OrderedLocusNames=SCAB_84891 {ECO:0000313|EMBL:CBG75436.1};
OS Streptomyces scabiei (strain 87.22).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=680198 {ECO:0000313|EMBL:CBG75436.1, ECO:0000313|Proteomes:UP000001444};
RN [1] {ECO:0000313|EMBL:CBG75436.1, ECO:0000313|Proteomes:UP000001444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=87.22 {ECO:0000313|EMBL:CBG75436.1,
RC ECO:0000313|Proteomes:UP000001444};
RX PubMed=20064060; DOI=10.1094/MPMI-23-2-0161;
RA Bignell D.R., Seipke R.F., Huguet-Tapia J.C., Chambers A.H., Parry R.J.,
RA Loria R.;
RT "Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic
RT cluster that contributes to plant-microbe interactions.";
RL Mol. Plant Microbe Interact. 23:161-175(2010).
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DR EMBL; FN554889; CBG75436.1; -; Genomic_DNA.
DR AlphaFoldDB; C9Z050; -.
DR STRING; 680198.SCAB_84891; -.
DR KEGG; scb:SCAB_84891; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_0_11; -.
DR Proteomes; UP000001444; Chromosome.
DR GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR CDD; cd05924; FACL_like_5; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:CBG75436.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001444}.
FT DOMAIN 24..408
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 462..538
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 553 AA; 59650 MW; F7D3D4BE8FB37629 CRC64;
MTGNPRASEV RRSTVEYNLA DLFESVVDVV PGRAALAYLD IPGTGAEHRL TYAELDAAAN
RIGHHLLDSG IRPGEHVGLH LYNGIEYLQT ALGCLKARIV PVNVNYRYVE EELVYLYRDA
DLAGLVFDAE FTERVAGALP RTEKLRHLVR VGTPAQDAPA LDVTAFAEAV AAASDGRGFP
ARSGDDQFII YTGGTTGMPK GVMWRQEDLF FSGLGGGAPT GEPVKSPEEL AERVAAGGDG
ITFFPTAPLM HGTSTLTAFI GFNFGQRVVI HRKFVPEEAL RTIEKEKVTS VSLVGDAMLR
PLIDALNGPM KGTDCSSLFS VSSSGAVMSE TVRQEFRALV PNAMLLNNFG SSESGFNGTA
TQDSGAGDGF RIRVHSRTRV VDPATYEPVP VGVPGRVAQR GHVPLGYYND PRKTAETFFE
RDGERWVLLG DMATVDEEGV VTVLGRGSQC INTGGEKVYP EEVEQALKAH PDVYDALVAG
VPDPRWGSHV AAVVQLREGA ARPSLEEIQT HCRTRLAGYK IPRRLVLAET IQRSPSGKAD
YRWARSVATA ADG
//
